Fig.1

The ROI of the T2/FLAIR mismatch sign of the entire tumor. Diffuse astrocytoma of the left frontal lobe with IDHMUT/1p/19q+, WHO grade Ⅱ. (a) Axial T2WI, the lesion showed high signal, clear boundary, and no obvious edema in the surrounding brain tissue; (b) Axial FLAIR, except for the edge high signal ring, most of the tumor area has relatively lower signal intensities compared with T2WI; (c) Axial T1 enhancement, no obvious enhancement of the lesion

Fig.2

The ROI of the T2/FLAIR mismatch sign in part of the tumor. The left temporal parietal insula oligodendroglioma with IDHMUT/1p/19q?, WHO grade Ⅱ. (a) Axial T2WI, the lesion showed mixed signals, the boundary was not clear, and there was a little edema in the surrounding brain tissue, some areas of the tumor showed high signal; (b) Axial FLAIR, the lesions are dominated by confounding signals. Some areas of the tumor showed relatively lower signal (except for obvious cystic degeneration, necrosis and edema); (c) Axial T1 enhancement, no obvious enhancement of the lesion in the mismatched area

Table 1

General clinical data of 19 patients with T2/FLAIR mismatch sign

Table 2

Comparison of the overall characteristics of the tumor area between the positive group and false positive group

Fig.3

Comparison of the quantitative parameters of the mismatch area between the positive group and false positive group. *p < 0.05, **p < 0.01

Fig.4

ROC curves of the quantitative parameters of mismatch regions for IDHMUT/1p/19q+ LGG prediction