Chinese Journal of Magnetic Resonance ›› 2015, Vol. 32 ›› Issue (1): 87-94.doi: 10.11938/cjmr20150110

Previous Articles     Next Articles

Structural Elucidation of D-Camphor and β-Cyclodextrin Inclusion Complex

ZHU Qing-ying*,HE Pei-zhi   

  1. Department of Chemistry, Huizhou College, Huizhou 516007, China
  • Received:2014-06-26 Revised:2015-01-08 Online:2015-03-05 Published:2015-03-05
  • About author:*Corresponding author:ZHU Qing-ying, Tel: +86-13516681806, E-mail: zqy-hz@126.com; zqy@hzu.edu.cn.

Abstract:

Inclusion complex of β-cyclodextrin (β-CD) and D-camphor was prepared from saturated solution with stirring. The stoichiometric ratio of the inclusion complex was found to be 1∶1, as indicated by the 1H NMR results. XRD and FTIR spectroscopy was used to probe the intermolecular interactions between D-camphor and β-CD. 1H ROESY NMR results showed that the bicyclo[2.2.1]-2-heptanone of D-camphor was located in the cavity of β-CD, and its methyl group was partially outside. Quantum chemical calculation was used to obtain minimized binding energy and optimized structure, suggesting the
presence of hydrogen bonding.

Key words: NMR, inclusion complex, β-cyclodextrin, D-camphor

CLC Number: