Complete Assignments of NMR Spectral Data of Three C19-Diterpenoid Alkaloids

doi:10.11938/cjmr20182694

Abstract

Abstract: C₁₉-diterpenoid alkaloids have complex and diverse structures, posing great challenges for nuclear magnetic resonance (NMR)-based structural elucidation. Three C₁₉-diterpenoid alkaloids, including taronenine E (1), chasmaconitine (2) and vilmorisine (3), were isolated from the roots of Aconitum taronense Fletcher et Lauener, and analyzed by various NMR spectroscopy methods (i.e., ¹H and ¹³C NMR, DEPT, ¹H-¹H COSY, HSQC and HMBC). Complete assignments of the NMR chemical shifts were obtained, providing a good reference for the further research of C₁₉-diterpenoid alkaloids.

Key words: C₁₉-diterpenoid alkaloids, Aconitum taronense Fletcher et Lauener, nuclear magnetic resonance (NMR), assignment

CLC Number:

O482.53

YIN Tian-peng, WANG Ya-rong, WANG Min, SHI Wen-zhi, ZHANG Zheng-qian, HE Sha-sha. Complete Assignments of NMR Spectral Data of Three C₁₉-Diterpenoid Alkaloids[J]. Chinese Journal of Magnetic Resonance, 2019, 36(3): 331-340.

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Complete Assignments of NMR Spectral Data of Three C₁₉-Diterpenoid Alkaloids

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