Structural Elucidation of D-Camphor and β-Cyclodextrin Inclusion Complex

doi:10.11938/cjmr20150110

Abstract

Abstract:

Inclusion complex of β-cyclodextrin (β-CD) and D-camphor was prepared from saturated solution with stirring. The stoichiometric ratio of the inclusion complex was found to be 1∶1, as indicated by the 1H NMR results. XRD and FTIR spectroscopy was used to probe the intermolecular interactions between D-camphor and β-CD. 1H ROESY NMR results showed that the bicyclo[2.2.1]-2-heptanone of D-camphor was located in the cavity of β-CD, and its methyl group was partially outside. Quantum chemical calculation was used to obtain minimized binding energy and optimized structure, suggesting the
presence of hydrogen bonding.

Key words: NMR, inclusion complex, β-cyclodextrin, D-camphor

CLC Number:

O636

ZHU Qing-ying*，HE Pei-zhi. Structural Elucidation of D-Camphor and β-Cyclodextrin Inclusion Complex[J]. Chinese Journal of Magnetic Resonance, 2015, 32(1): 87-94.

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