Chinese Journal of Magnetic Resonance

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 Spectral Analysis and Structural Elucidation of Atorvastatin Lactone

WU Chun-li*,LI Jie-ming,WEI Hui-jie,JIANG Yue-ming,HANG Ye,CHEN Xin-li,ZHU Kai

 
 
  

  1. School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China
  • Received:2013-05-07 Revised:2013-09-05 Online:2014-06-05 Published:2014-06-05
  • About author:*Corresponding author:WU Chun-li, Tel: 0371-68781049,E-mail:kedi2009@126.com.

Abstract:

Ultraviolet spectrum, infrared spectrum, mass spectra and nuclear magnetic resonance spectra of atorvastatin lactone were collected and interpreted. All the NMR signals were assigned. Based on the mass spectral data, the possible fragmentation pathways were discussed. The infrared spectrum was used to analyze the types of vibration of the functional groups in this compound. The structure of the compound was determined.

Key words: NMR, assignment, chemical shift, atorvastatin lactone, structural elucidation

CLC Number: