Structural Elucidation of Addition Product from 3-Oxoxylose and Nitromethane

Chinese Journal of Magnetic Resonance

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Structural Elucidation of Addition Product from 3-Oxoxylose and Nitromethane

ZHANG En，ZHANG Zhao，SUN Wei，XU Jin-Mei，GAO Jie，LI Xiao-Chen，LIU Hong-Min*

New Drug Research ＆ Development Center, School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China

Received:2013-05-08 Revised:2013-06-12 Online:2014-06-05 Published:2014-06-05
About author:*Corresponding author：LIU Hong-min, Tel: 0371-67781739，E-mail：liuhm@zzu.edu.cn.
Supported by:
国家自然科学基金资助项目(81172937, U1204206)，教育部新教师基金资助项目(20114101120013)及中国博士后基金资助项目(20100480857, 201104376)．

Abstract

Abstract:

A new nitro sugar compound 1, 2-O-isopropylidene-3-C-nitromethyl-4- methenyl-α-D-xylofuranose (2) and a known nitro sugar compound 1,2-O-isopropylidene- 3-C-nitromethyl-5-(p-methylbenzenesulfonyl)-α-D-xylofuranose (1) were synthesized from 3-oxoxylose and nitromethane by Henry reaction. The compound 2 was characterized using NMR spectroscopy techniques, including one-dimensional ¹H and ¹³C NMR, ¹H-¹H COSY, HSQC and HMBC. The NMR signals were assigned. The molecular structure of compound 2 was determined.

Key words: NMR, assignment, 3-oxoxylose, nitro sugar

CLC Number:

O482.53

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Structural Elucidation of Addition Product from 3-Oxoxylose and Nitromethane

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