Chinese Journal of Magnetic Resonance ›› 2004, Vol. 21 ›› Issue (3): 365-369.

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A NMR STUDY OF PHENYLPIPERAZINE DERIVATIVES

 XIAO Zhi-Hui1, YUAN Mu2, HUANG Jian-She1, WU Jun1   

  1. 1.Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301,China; 2.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002,China
  • Received:2004-02-19 Revised:2004-04-05 Online:2004-09-05 Published:2004-09-05
  • Supported by:

    国家自然科学基金资助项目(30060087).

Abstract:

Having the potential of being used as α1-adrenoceptor antagonist and new antihypertensive drugs, ten phenylpiperazine derivatives were synthesized, and their structures were determined by 1H NMR, 13C NMR, HMBC, HSQC and 1H-1H DQF-COSY. The 1H and 13C chemical shifts of these compounds were assigned. The relationship between the substitute groups and the 13C chemical shifts was discussed.

Key words: NMR, assignments, chemical shift, phenylpiperazine

CLC Number: