A Classification Method for Cerebral Aneurysms in TOF-MRA Based on Improved 3D ResNet50 Model

doi:10.11938/cjmr20243119

Abstract

Abstract:

The irregular morphology of cerebral aneurysms, especially the presence of a daughter sac, is a crucial risk factor for aneurysm rupture. Clinical assessment of daughter sac relies mainly on image reconstruction by time of flight-magnetic resonance angiography (TOF-MRA) and judgment based on physicians' vision and experience, which limits the efficiency and accuracy of diagnosis. In this paper, we propose an improved parallel multiscale fusion attention network (PMAF-Net) based on 3D ResNet50 for classification. PMAF-Net uses multi-scale convolution and weighted fusion channel and spatial attention weights to enhance the feature extraction capability. The experiment used 291 cases of TOF-MRA data, including 128 cases in the training set, 32 cases in the validation set, and 131 cases in the test set. Compared with other classification networks, PMAF-Net performs best on the test set, with the accuracy of 83.97%, recall of 84.48%, precision of 80.33%, and F1-score of 0.823 5, and the receiver operating characteristic curve (ROC) also reflects the model's optimal classification performance (AUC of 0.900 8). The results show that the network can identify daughter sac type aneurysms more accurately, which is expected to support the assessment and quantification of the risk of aneurysm rupture.

Key words: TOF-MRA, daughter sac of cerebral aneurysms, multiscale convolution attention, automatic classification, deep learning

CLC Number:

O482.53

XUE Peiyang, GENG Chen, LI Yuxin, BAO Yifang, LU Yucheng, DAI Yakang. A Classification Method for Cerebral Aneurysms in TOF-MRA Based on Improved 3D ResNet50 Model[J]. Chinese Journal of Magnetic Resonance, 2025, 42(1): 56-66.

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组别	训练集	验证集	测试集
患者数量	128	32	131
男性/女性	56/72	12/20	71/60
年龄（岁）	56±12	58±9	62±14
正常动脉瘤/子瘤型动脉瘤	78/50	19/13	76/55
动脉瘤大小（mm）	6.75±5.23	6.04±4.21	6.92±6.27
小型动脉瘤（<5mm）/子瘤	46/10	11/4	47/9
中型动脉瘤（5≤最大径<15mm）/子瘤	74/37	19/8	81/46
大型动脉瘤（15≤最大径<25mm）/子瘤	8/3	2/1	3/0

采集设备	重复时间	回波时间	图像分辨率	层厚	翻转角	采集矩阵	扫描时间
GE 3.0T	25 ms	5.7 ms	1024×1024×240	1.2 mm	20˚	320×256	3min22s
SIEMENS 3.0T	21 ms	3.6 ms	512×512×128	0.9 mm	18˚	256×197	2min53s
Philips 3.0T	18 ms	3.5 ms	512×512×128	1.0 mm	20˚	308×203	2min22s

类别 Category	精确率 Precision	召回率 Recall	F1分数 F1_Score
子瘤型动脉瘤（有子瘤）	80.33%	84.48%	0.8235
正常动脉瘤（无子瘤）	87.14%	83.56%	0.8531
平均	83.74%	84.02%	0.8383

亚组分析 Subgroup analysis	准确率 Accuracy	召回率 Recall	精确率 Precision	F1分数 F1_Score
总体性能	83.97%	84.48%	80.33%	0.8235
按最大径划分
小型动脉瘤（47）	80.85%	77.78%	50.00%	0.6087
中型动脉瘤（81）	85.19%	84.78%	88.64%	0.8667
大型动脉瘤（3）	100.00%	100.00%	100.00%	1.0000

模型 Models	准确率 Accuracy	召回率 Recall	精确率 Precision	F1分数 F1_Socre
ResNet18^[23]	74.81%	60.34%	77.78%	0.6796
ResNet50^[20]	72.52%	74.14%	67.19%	0.7049
DenseNet^[26]	67.94%	68.97%	62.50%	0.6557
MobileNet^[27]	77.86%	81.03%	72.31%	0.7642
EfficientNet^[28]	72.52%	65.52%	70.37%	0.6786
PMAF-Net（本文）	83.97%	84.48%	80.33%	0.8235