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数学物理学报, 2021, 41(6): 1864-1870 doi:

论文

一类非局部时滞的SVIR反应扩散模型的全局吸引性

杨瑜,

上海立信会计金融学院统计与数学学院 上海 201209

Global Attractivity of a Nonlocal Delayed and Diffusive SVIR Model

Yang Yu,

School of Statistics and Mathematics, Shanghai Lixin University of Accounting and Finance, Shanghai 201209

收稿日期: 2021-01-11  

Received: 2021-01-11  

作者简介 About authors

杨瑜,E-mail:yangyu@lixin.edu.cn , E-mail:yangyu@lixin.edu.cn

Abstract

In this paper, by using Lyapunov functional, we prove the global attractivity of the endemic equilibrium for a nonlocal delayed and diffusive SVIR model when R0>1, which cover and improve some known results.

Keywords: SVIR model ; Spatial heterogeneity ; Lyapunov functional ; Global attractivity

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本文引用格式

杨瑜. 一类非局部时滞的SVIR反应扩散模型的全局吸引性. 数学物理学报[J], 2021, 41(6): 1864-1870 doi:

Yang Yu. Global Attractivity of a Nonlocal Delayed and Diffusive SVIR Model. Acta Mathematica Scientia[J], 2021, 41(6): 1864-1870 doi:

1 引言

最近, 文献[1]考虑了如下一类非局部时滞的SVIR反应扩散模型:

{St=(dS(x)S)+λ(x)β1(x)SI(μ(x)+α(x))S, t>0, xΩ,Vt=(dV(x)V)+α(x)Sβ2(x)VI(μ(x)+γ(x))V, t>0, xΩ,It=(dI(x)I)+ΩG(τ,x,y)[β1(y)S(tτ,y)+β2(y)V(tτ,y)]I(tτ,y)dy(μ(x)+δI(x))I, t>0, xΩ,Rt=(dR(x)R)+γ(x)V+δI(x)Iμ(x)R, t>0, xΩ,[dS(x)S]ν=[dV(x)V]ν=[dI(x)I]ν=[dR(x)R]ν=0, t>0, xΩ,
(1.1)

其中S(t,x), V(t,x), I(t,x)R(t,x)分别表示时刻t和空间位置x处易感个体、疫苗接种个体、染病个体和康复个体的密度. 是梯度算子. G是与(dE())(μ()+δE())和Neumann边值条件相关的格林函数. ΩRn是具有光滑边界Ω的有界区域.所有的参数都是连续和严格正的.

由于系统(1.1)的第四个方程与前三个方程是解耦的, 故只需考虑如下系统:

{St=(dS(x)S)+λ(x)β1(x)SI(μ(x)+α(x))S, t>0, xΩ,Vt=(dV(x)V)+α(x)Sβ2(x)VI(μ(x)+γ(x))V, t>0, xΩ,It=(dI(x)I)+ΩG(τ,x,y)[β1(y)S(tτ,y)+β2(y)V(tτ,y)]I(tτ,y)dy(μ(x)+δI(x))I, t>0, xΩ,[dS(x)S]ν=[dV(x)V]ν=[dI(x)I]ν=0, t>0, xΩ.
(1.2)

由文献[2]知, 当基本再生数R0<1时, 系统(1.2)的唯一的无病平衡态是全局渐近稳定的; 当R0>1时, 系统(1.2)至少存在一个正平衡态并且系统是一致持续生存的.由于空间异质的影响, 研究系统(1.2)的正平衡态的全局吸引性是非常困难的.注意到, 文献[2]利用波动引理的方法讨论了一类非局部时滞的捕食-食饵反应扩散模型的正平衡点的全局吸引性.随后, 很多学者利用该方法讨论了具有非局部时滞的不同类型传染病模型的正平衡点的全局吸引性, 见文献[3-6].

假定系统(1.2)中的参数都是常数.由G(τ,x,y)是与dEΔ(μ+δE)和Neumann边值条件相关的格林函数及Fourier变换可知

G(τ,x,y)=e(μ+δE)τ(14πdEτ)nexp(|xy|24dEτ).

定义

G(dEτ,x,y)=(14πdEτ)nexp(|xy|24dEτ),

G(τ,x,y)=e(μ+δE)τG(dEτ,x,y).

G(τ,x,y)τ=dEΔG(τ,x,y)(μ+δE)G(τ,x,y),

G(dEτ,x,y)τ=dEΔG(dEτ,x,y),

G(dEτ,x,y)是与dE和Neumann边值条件相关的格林函数且ΩG(dEτ,x,y)dy=1.因此, 系统(1.2)中的参数都是常数时可化为如下系统:

{St=dSΔS+λβ1SI(μ+α)S, t>0, xΩ,Vt=dVΔV+αSβ2VI(μ+γ)V, t>0, xΩ,It=dIΔI+e(μ+dE)τΩG(dEτ,x,y)[β1S(tτ,y)+β2V(tτ,y)]I(tτ,y)dy(μ+δI)I, t>0, xΩ,Sν=Vν=Iν=0, t>0, xΩ.
(1.3)

目前, 有关系统(1.3)的正平衡点的全局吸引性方面的结果还没有.最近, 文献[7]通过构造合适的Lyapunov泛函讨论一类非局部时滞的蓝舌病反应扩散模型的正平衡点的全局吸引性.受文献[7]的启发, 本文通过构造Lyapunov泛函研究系统(1.3)的正平衡点的全局吸引性.关于Lyapunov泛函的构造方法, 见文献[8-10].

本文结构安排如下:第二节给出一些预备知识.第三节讨论当基本再生数R0>1时系统(1.3)的正平衡点的全局吸引性.最后, 给出简要的结论.

2 预备知识

τ0, 定义Cτ:=C([τ,0],X), 范数为||ψ||=max其中 {\Bbb X}: = C(\bar{\Omega}, {{\Bbb R}} ^{3}) 是具有范数 ||\psi(\cdot)||_{{\Bbb X}} 的Banach空间.进一步, 定义 {\Bbb X}^{+}: = C(\bar{\Omega}, {{\Bbb R}} _{+}^{3}) C_{\tau}^{+}: = C([-\tau, 0], {\Bbb X}^{+}) .

由文献[1]的定理6.1有

定理2.1  对 \forall\ \psi\in C_{\tau}^{+} , 系统(1.3)在 [0, \infty) 上存在唯一的解 {\bf u}(t, \cdot, \psi) , 且解半流 \Psi(t) = {\bf u}_{t}(\cdot): C_{\tau}^{+}\rightarrow C_{\tau}^{+} , t\geq0 C_{\tau}^{+} 上有一个全局紧吸引子.

易知, 系统(1.3)总是存在一个无病平衡点 E_0 = (S^0, V^0, 0) , 其中

S^0 = \frac{\lambda}{\mu+\alpha}, \quad V^0 = \frac{\alpha\lambda}{(\mu+\alpha)(\mu+\gamma)}.

而且系统(1.3)的基本再生数

{\cal R}_0 = {\rm e}^{-(\mu+\delta_{E})\tau}\frac{\beta_1S^0+\beta_2V^0}{\mu+\delta_{I}}.

由文献[11]知, 当 {\cal R}_0>1 时, 系统(1.3)有唯一的正平衡点 E^* = (S^*, V^*, I^*) , 其中

S^* = \frac{\lambda}{\beta_1I^*+\mu+\alpha}, \quad V^* = \frac{\alpha S^*}{\beta_2I^*+\mu+\gamma},

a(I^*)^{2}+bI^*+c = 0,

这里

a = \beta_1\beta_2, \quad b = \beta_1(\mu+\gamma)+\beta_2(\mu+\alpha)-{\rm e}^{-(\mu+\delta_{E})\tau}\frac{\beta_1\beta_2\lambda}{\mu+\delta_{I}},

c = (\mu+\alpha)(\mu+\gamma)(1-{\cal R}_0).

再由文献[1]的推论6.7有

定理2.2   (ⅰ)若 {\cal R}_0<1 , 则无病平衡点 E_{0} C_{\tau}^{+} 内是全局吸引的.

(ⅱ) 若 {\cal R}_0>1 , 则存在一个常数 \varrho>0 使得对 \forall\ \psi\in C_{\tau}^{+} 满足 \psi_3(0, \cdot)\not\equiv0 , 关于 x\in \overline{\Omega} 一致成立

\liminf \limits_{t\rightarrow +\infty}S(t, x)\geq\varrho, \ \; \; \liminf \limits_{t\rightarrow +\infty}V(t, x)\geq\varrho, \ \; \; \liminf \limits_{t\rightarrow +\infty}I(t, x)\geq\varrho.

3 全局吸引性

下面给出本文的主要结果.

定理3.1  若 {\cal R}_0>1 , 则对 \forall\ \psi\in C_{\tau}^{+} 满足 \psi_3(0, \cdot)\not\equiv0 , 关于 x\in \overline{\Omega} 一致成立

\lim\limits_{t\rightarrow \infty}{\bf u}(t, x;\psi) = {\bf u}^{*},

其中 {\bf u}^{*} = (S^*, V^*, I^*) .

  定义 \omega(\psi) 是半流 \Psi(t) 的轨道 \gamma^{+}(\psi) \omega -极限集.定义集合

{\Bbb H}: = \left\{\psi\in C_{\tau}^{+}:\psi_{i}(0, x)>0, \ \forall x\in\bar{\Omega}, \ i = 1, 2, 3\right\}.

由定理2.1和2.2(ⅱ)可知, \omega(\psi)\subset{\Bbb H} .为方便讨论, 记 {\cal X} = {\cal X}(t, x), \ \forall {\cal X}\in\{S, V, I\}.

构造Lyapunov泛函 {\Bbb V}:{\Bbb H}\rightarrow {{\Bbb R}} 如下:

\begin{eqnarray*} {\Bbb V}(t) = \int_{\Omega}({\Bbb V}_1(t, x)+{\Bbb V}_2(t, x)){\rm d}x, \end{eqnarray*}

其中

\begin{eqnarray*} {\Bbb V}_1(t, x)& = & S^* g\left(\frac{S}{S^*}\right)+V^* g\left(\frac{V}{V^*}\right) +{\rm e}^{(\mu+\delta_{E})\tau}I^* g\left(\frac{I}{I^*}\right), \\ {\Bbb V}_2(t, x)& = & \beta_1S^* I^*\int_{-\tau}^{0}\int_{\Omega}G(d_{E}(-\theta), x, y)g\left(\frac{S(t+\theta, y)I(t+\theta, y)}{S^* I^*}\right){\rm d}y{\rm d}\theta \\ &&+\beta_2V^* I^*\int_{-\tau}^{0}\int_{\Omega}G(d_{E}(-\theta), x, y)g\left(\frac{V(t+\theta, y)I(t+\theta, y)}{V^* I^*}\right){\rm d}y{\rm d}\theta, \end{eqnarray*}

g(x) = x-1-\ln x , x>0 .显然, x>0 g(x)\geq 0 \min\limits_{x>0}g(x) = g(1) .

注意到

\lambda = \beta_1S^* I^*+(\mu+\alpha)S^*, \ \alpha S^* = \beta_2V^* I^*+(\mu+\gamma)V^*

{\rm e}^{-(\mu+d_{E})\tau}(\beta_1S^*+\beta_2V^*) = \mu+\delta_{I}.

通过计算得

\begin{eqnarray*} \frac{\partial{\Bbb V}_1(t, x)}{\partial t} & = &\left(1-\frac{S^*}{S}\right)(d_{S}\triangle S+(\mu+\alpha)S^*-(\mu+\alpha)S+\beta_1S^* I^*-\beta_1SI)\\ && +\left(1-\frac{V^*}{V}\right)(d_{V}\triangle V+\alpha(S-S^*)+(\mu+\gamma)(V^*-V)+\beta_2V^* I^*-\beta_2VI)\\ & &+{\rm e}^{(\mu+\delta_{E})\tau}\left(1-\frac{I^*}{I}\right)\left(d_{I}\Delta I-{\rm e}^{-(\mu+\delta_{E})\tau} (\beta_1S^*+\beta_2V^*)I\right.\\ &&\left.+{\rm e}^{-(\mu+\delta_{E})\tau}\int_{\Omega}G(d_{E}\tau, x, y)[\beta_1S (t-\tau, y)+\beta_2V(t-\tau, y)]I(t-\tau, y){\rm d}y\right)\\ & = & A-\mu S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{S}{S^*}\right)\right)+\alpha S^*\left(1-\frac{S^*}{S} -\frac{SV^*}{S^* V}+\frac{V^*}{V}\right)\\ && -(\mu+\gamma)V^*\left(g\left(\frac{V^*}{V}\right)+g\left(\frac{V}{V^*}\right)\right)\\ && +\beta_1S^* I^*\left(2-\frac{SI}{S^*I^*}-\frac{S^*}{S}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{S(t-\tau, y)I(t-\tau, y)} {S^* I}{\rm d}y\right)\\ &&+\beta_2V^* I^*\left(2-\frac{VI}{V^*I^*}-\frac{V^*}{V}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{V(t-\tau, y)I(t-\tau, y)} {V^* I}{\rm d}y\right)\\ &&+\int_{\Omega}G(d_{E}\tau, x, y)[\beta_1S(t-\tau, y)+\beta_2V(t-\tau, y)]I(t-\tau, y){\rm d}y, \end{eqnarray*}

其中

A = \frac{d_{S}(S-S^*)}{S}\triangle S+\frac{d_{V}(V-V^*)}{V}\triangle V+{\rm e}^{(\mu+\delta_{E})\tau}\frac{d_{I}(I-I^*)}{I}\triangle I.

\begin{eqnarray*} \frac{\partial{\Bbb V}_2(t, x)}{\partial t} & = &\beta_1S^* I^*\left[g\left(\frac{SI}{S^* I^*}\right)-\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I^*}\right){\rm d}y\right]\\ &&+\beta_2V^* I^*\left[g\left(\frac{VI}{V^* I^*}\right)-\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I^*}\right){\rm d}y\right]\\ & = &\beta_1S^* I^*\left[\frac{SI}{S^* I^*}-\ln\frac{SI}{S^* I^*}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I^*}{\rm d}y\right.\\ &&\left.+\int_{\Omega}G(d_{E}\tau, x, y)\ln\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I^*}{\rm d}y\right]\\ &&+\beta_2V^* I^*\left[\frac{VI}{V^* I^*}-\ln\frac{VI}{V^* I^*}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I^*}{\rm d}y\right.\\ &&\left.+\int_{\Omega}G(d_{E}\tau, x, y)\ln\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I^*}{\rm d}y\right]. \end{eqnarray*}

进一步, 有

\begin{eqnarray*} &&\frac{\partial({\Bbb V}_1(t, x)+{\Bbb V}_2(t, x))}{\partial t}\\ & = & A-\mu S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{S}{S^*}\right)\right)-(\mu+\gamma)V^* g\left(\frac{V^*}{V}\right)-(\mu+\gamma)V^* g\left(\frac{V}{V^*}\right)\\ &&+\alpha S^*\left(g\left(\frac{V^*}{V}\right)-g\left(\frac{S^*}{S}\right)-g\left(\frac{SV^*}{S^* V}\right)\right)\\ &&+\beta_1S^* I^*\left(2-\frac{S^*}{S}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I}{\rm d}y\right.\\ &&\left.-\ln\frac{SI}{S^* I^*}+\int_{\Omega}G(d_{E}\tau, x, y)\ln\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I^*}{\rm d}y\right)\\ &&+\beta_2V^* I^*\left(2-\frac{V^*}{V}-\int_{\Omega}G(d_{E}\tau, x, y)\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I}{\rm d}y\right.\\ &&\left.-\ln\frac{VI}{V^* I^*}+\int_{\Omega}G(d_{E}\tau, x, y)\ln\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I^*}{\rm d}y\right)\\ & = & A-\mu S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{S}{S^*}\right)\right)-(\mu+\gamma)V^* g\left(\frac{V}{V^*}\right)\\ &&-\alpha S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{SV^*}{S^* V}\right)\right)\\ &&-\beta_1S^* I^*\left(g\left(\frac{S^*}{S}\right)+\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I}\right){\rm d}y\right)\\ &&-\beta_2V^* I^*\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{V(t-\tau, y)I(t-\tau, y)}{V^* I}\right){\rm d}y. \end{eqnarray*}

由于 \int_{\Omega}\Delta \kappa {\rm d}x = 0 \int_{\Omega}\frac{\Delta \kappa}{\kappa}{\rm d}x = \int_{\Omega}\frac{\|\nabla\kappa\|^2}{\kappa^2}{\rm d}x\geq 0 , 故

\begin{eqnarray} \frac{{\rm d}{\Bbb V}(t)}{{\rm d}t}& = &\int_{\Omega}\frac{\partial({\Bbb V}_1(t, x)+{\Bbb V}_2(t, x))}{\partial t}{\rm d}x {}\\ &\leq&-\int_{\Omega}\left[\mu S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{S}{S^*}\right)\right) +\alpha S^*\left(g\left(\frac{S^*}{S}\right)+g\left(\frac{SV^*}{S^*V}\right)\right)\right.{}\\ &&\left.+(\mu+\gamma)V^* g\left(\frac{V}{V^*}\right)+\beta_1S^* I^*g\left(\frac{S^*}{S}\right)\right]{{\rm d}x}{}\\ &&-\beta_1S^* I^*\int_{\Omega}\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{S(t-\tau, y)I(t-\tau, y)}{S^* I}\right){\rm d}y{\rm d}x{}\\ &&-\beta_2V^* I^*\int_{\Omega}\int_{\Omega}G(d_{E}\tau, x, y)g\left(\frac{V(t-\tau, y)I(t-\tau, y)} {V^* I}\right){\rm d}y{\rm d}x: = {\cal U}_{\psi}(t). \end{eqnarray}
(3.1)

t\geq0 , {\Bbb V}({\bf u}_{t}(\psi)) 是非增和有下界的.因此, 存在一个常数 {\cal G}>0 使得 \lim\limits_{t\rightarrow \infty}{\Bbb V}({\bf u}_{t}(\psi)) = {\cal G}. 进一步, 存在一个序列 l_{n}\rightarrow \infty 使得在 {\Bbb H} 内有 \lim\limits_{n\rightarrow \infty}{\bf u}_{l_n}(\psi) = \varphi .这意味着对 \forall\varphi\in\omega(\psi) {\Bbb V}(\varphi) = {\cal G} .故当 t\geq0 时, 由 {\bf u}_t(\varphi)\in\omega(\psi) {\Bbb V}({\bf u}_t(\varphi)) = {\cal G} .故有 \frac{{\rm d}{\Bbb V}({\bf u}_t(\varphi))}{{\rm d}t} = 0 .根据不等式(3.1)得

0 = \frac{{\rm d}{\Bbb V}({\bf u}_t(\varphi))}{{\rm d}t}\leq{\cal U}_{\varphi}(t)\leq0.

因此, t\geq0 时有 {\cal U}_{\varphi}(t) = 0 .由系统(1.3)知, 对 \forall\ t\geq\tau {\bf u}_t(\varphi) = {\bf u}^* . t\geq\tau 时, 由于 \varphi\in\omega(\psi) 是任意的, 故得 {\bf u}_t(\omega(\psi)) = {\bf u}^* .利用 \omega -极限集的不变性, 得 \omega(\psi) = {\bf u}_{\tau}(\omega(\psi)) = {\bf u}^* , 即 \lim\limits_{t\rightarrow \infty}{\bf u}(t, x;\psi) = {\bf u}^{*} .

4 结论

当不考虑扩散和空间异质时, 系统(1.3)即为如下的时滞系统:

\begin{eqnarray} \left\{ \begin{array}{ll} { } \frac{{\rm d}S(t)}{{\rm d}t} = \lambda-\beta_1SI-(\mu+\alpha)S, \\ { } \frac{{\rm d}V(t)}{{\rm d}t} = \alpha S-\beta_2VI-(\mu+\gamma)V, \\ { } \frac{{\rm d}I(t)}{{\rm d}t} = {\rm e}^{-(\mu+d_{E})\tau}[\beta_1S(t-\tau)+\beta_2V(t-\tau)]I(t-\tau)-(\mu+\delta_{I})I. \end{array} \right. \end{eqnarray}
(4.1)

有关系统(4.1)的正平衡点的全局吸引性的结果可参见文献[12-14].当时滞 \tau = 0 时, 参见文献[15].

当不考虑固定潜伏期时, 系统(1.3)即为如下的反应扩散系统:

\begin{eqnarray} \left\{ \begin{array}{ll} { } S_{t} = d_{S}\Delta S+\lambda-\beta_1SI-(\mu+\alpha)S, \ t>0, \ x\in\Omega, \\ { } V_{t} = d_{V}\Delta V+\alpha S-\beta_2VI-(\mu+\gamma)V, \ t>0, \ x\in\Omega, \\ { } I_{t} = d_{I}\Delta I+\beta_1SI+\beta_2VI-(\mu+\delta_{I})I, \ t>0, \ x\in\Omega, \\ { } \frac{\partial S}{\partial{\bf \nu}} = \frac{\partial V}{\partial{\bf \nu}} = \frac{\partial I}{\partial{\bf \nu}} = 0, \ t>0, \ x\in\partial\Omega. \end{array} \right. \end{eqnarray}
(4.2)

系统(4.2)的正平衡点的全局吸引性的结果见文献[16].

\beta_2(x) = 0 , 系统(1.2)已被文献[17]讨论过.进一步, 文献[18]在文献[17]的基础上考虑时间异质并推广了文献[17]中的结果.注意到文献[17, 18]中并未讨论正平衡态的全局吸引性.对于空间异质的反应扩散传染病模型, 研究其正平衡态的全局吸引性是非常困难的.当 {\cal R}_0>1 时, 本文利用Lyapunov泛函的方法讨论了系统(1.3)的正平衡点的全局吸引性.

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