NMR Analysis of By-Products in Imidacloprid Production

Abstract

Abstract:

In this paper, qualitative and quantitative NMR techniques were used to analyze samples obtained from imidacloprid production. Two-dimensional DOSY spectra demonstrated the samples contained two by-products. One-dimensional (i.e., ¹H and ¹³C NMR and DEPT) and two-dimensional (i.e., 1H-1H COSY, HSQC and HMBC) NMR techniques were used to assign the chemical shifts of the by-products, which were finally determined to be 1,1-imorpholinopropane and N-(1-propenyl) morpholine. Finally a quantitative 13C NMR method was developed to measure the contents of by-products quantitatively.

Key words: NMR, structure analysis, quantification, DOSY, imidacloprid

CLC Number:

O482.53

ZHANG Feng-min1，YU Hua-guang2. NMR Analysis of By-Products in Imidacloprid Production[J]. Chinese Journal of Magnetic Resonance.

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