Chinese Journal of Magnetic Resonance ›› 2011, Vol. 28 ›› Issue (3): 383-389.

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Synthesis and Spectroscopic Characterization of a Novel 1, 5-Dibenzodiazepine Derivative

 WANG Lu1*, PAN Xiang-Qiang2, CAI Jing-Jing2, ZU Jian-Ping2   

  1. 1. Testing and Analysis Center, Soochow University, Suzhou 215123, China;
    2. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
  • Received:2010-12-07 Revised:2011-01-19 Online:2011-09-05 Published:2011-09-05
  • Supported by:

    国家自然科学基金资助项目(20772088).

Abstract:

Gallium (III) triflate-catalyzed reaction between o-phenylenediamine and ethyl propiolate under solvent-free and ultrasonic irradiation conditions produced a novel 1, 5-benzodiazepine derivative with a yield rate of 88%. Complete assignment of the 1H  and 13C NMR chemical shift of the compound was obtained using 2D NMR techniques, including DEPT, 1H-1H COSY, 1H-13C HMQC and 1H-13C HMBC. Mass fragmentation pathway was proposed based on the high resolution MS spectrum of the compound.

Key words: NMR, assignment, 2D NMR, TOF MS, 1, 5-benzodiazepine derivative, Ga(OTf)3

CLC Number: