NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine

Chinese Journal of Magnetic Resonance ›› 2009, Vol. 26 ›› Issue (1): 111-119.

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NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine

ZHANG Pei-xuan¹; LI Jian-feng²; WEI Ya-bing^1*; SHEN Jing-shan²

(1.College of Matherials Science and Engineering, Nanjing University of Technology, Nanjing 210009, China; 2.Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China)

Received:2008-06-10 Revised:2008-08-15 Online:2009-03-05 Published:2009-12-05
Contact: WEI Ya-bing

Abstract

Abstract: NMR (¹H NMR, ¹³C NMR, ¹H-¹H COSY, HSQC and HMBC) and mass spectra of a fluorine derivative of tetrahydroberberine were reported and interpreted. The NMR signals were assigned and the substituted positions for the fluorine atom was identified. The structure of the compound was determined with the spectral data. The probably fragmentation pathways of the compound were also discussed.

Key words: nuclear magnetic resonance, structure elucidation, mass spectrometry, fluoro tetrahydroberberine

CLC Number:

O641

ZHANG Pei-xuan¹; LI Jian-feng²; WEI Ya-bing^1*; SHEN Jing-shan². NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine[J]. Chinese Journal of Magnetic Resonance, 2009, 26(1): 111-119.

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NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine

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