Reconstruction of Displacement Field of Left Ventricle Combined with Biomechanical Model

doi:10.11938/cjmr20212898

Abstract

Abstract:

The left myocardium is the strongest cardiac muscle, representing the ability of heart to pump arterial blood throughout the body. Quantitative analysis of the contractive motion of left ventricle (LV) stands an important approach to diagnose cardiovascular diseases such as myocardial infarction. This paper utilized a biomechanical model describing the material of left myocardium to reconstruct the displacement field of LV. The mechanical model was used as an interpolation term, which was incorporated into the Bayesian estimation framework with the displacement field observed by cardiac cine magnetic resonance (CCMR) image, and the equation of displacement field was solved by finite element method. Functional parameters of LV were compared between the weak (46 cases) and normal (55 cases) ejection fraction groups of LV in the experiment. Significant differences in radial and circumferential displacement and velocity, strain and strain rate were observed between the two groups (p < 0.001), which proved that the method could effectively distinguish whether the motion of LV is normal or not. The experimental results are also highly correlated with the functional parameters of LV measured by CVI software, indicating that the method will facilitate the diagnosis of cardiovascular diseases.

Key words: left ventricle, displacement field, biomechanical model, cardiac cine magnetic resonance image

CLC Number:

TP391

Jian-sheng LIN,Li-jia WANG. Reconstruction of Displacement Field of Left Ventricle Combined with Biomechanical Model[J]. Chinese Journal of Magnetic Resonance, 2022, 39(1): 72-86.

Figures/Tables 11

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Table 1

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左心室功能参数	径向方向（峰值）				圆周方向（峰值）
左心室功能参数	RD/mm	RS/%	RV/(mm/s)	RSR/s^?1	CD/mm	CS/%	CV/(mm/s)	CSR/s^?1
射血正常	4.86±1.10	20.30±6.50	28.15±8.28	1.40±0.68	?3.09±0.71	?19.43±5.61	?18.19±5.34	?1.22±0.52
射血无力	3.29±0.92	11.62±5.65	19.69±5.60	0.78±0.32	?2.05±0.61	?10.86±4.63	?12.62±3.58	?0.63±0.24
p值	1.46e-11	2.04e-10	5.24e-08	1.45e-07	7.67e-12	6.40e-13	2.86e-08	2.06e-10

约束条件	径向方向（峰值）				圆周方向（峰值）
约束条件	RD/mm	RS/%	RV/(mm/s)	RSR/s^?1	CD/mm	CS/%	CV/(mm/s)	CSR/s^?1
无约束	4.07±0.97	21.03±6.89	24.83±6.45	1.35±0.49	?2.31±0.56	?13.06±6.56	?14.07±3.63	?1.19±0.88
平滑约束	4.23±0.96	18.76±5.05	25.72±6.48	1.10±0.35	?2.28±0.58	?10.51±3.68	?14.25±3.58	?0.76±0.33
模型约束	4.08±1.01	15.96±6.08	23.92±6.94	1.09±0.50	?2.57±0.66	?15.15±5.12	?15.40±4.46	?0.93±0.38

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