Chinese Journal of Magnetic Resonance

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Spectroscopic Characterization of Orlistat

CHEN Zai-xin*,YU Shui-tao,XIA Zheng-jun   

  1. R&D Center, Jiangsu Yabang Pharmaceutical Group, Changzhou 213200, China
  • Received:2013-04-08 Revised:2013-07-13 Online:2013-12-05 Published:2013-12-05
  • About author:*Corresponding author: Chen Zai-xin, Tel: 051982313163,E-mail: zaixin_chen@163.com.

Abstract:

Orlistat is a potent and specific inhibitor of gastric and pancreatic lipases. The structure of orlistat was identified by a series of spectroscopic techniques including NMR, UV and IR. The 1H  and 13C NMR signals of orlistat were assigned by DEPT, COSY, HMBC and HSQC.

Key words: NMR, assignment, infrared, ultraviolet, orlistat, structure

CLC Number: