Chinese Journal of Magnetic Resonance

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Spectral Analysis and Structural Elucidation of Emtricitabine

CHEN Shi-yun1,  HE Yong2, YU San-xi2,GAO Yong-hao2, JIANG Hao2, WU Zong-hao2*   

  1. 1. Department of Chemical and Materials Engineering, Hefei University, Hefei 230601,China; 
    2. Hefei Huafang Pharmaceutical Science & Technology Co., Ltd., Hefei 230088, China
  • Received:2012-12-08 Revised:2013-03-19 Online:2013-09-05 Published:2013-09-05
  • About author:*Corresponding author: Wu Zong-hao, Tel: 13956050528, E-mail:hfsci@163.com.

Abstract:

The spectral data of Emtricitabine were reported, including UV, IR, NMR (1H NMR, 1H-1H COSY, 13C NMR, DEPT, HMQC and HMBC) and MS data. The NMR signals were assigned. The infrared spectrum was analyzed to derive the types of vibrations of the functional groups in this compound. The molecular structure of emtricitabine was determined.

Key words: NMR, assignment, Emtricitabine, structural identification

CLC Number: