Chinese Journal of Magnetic Resonance ›› 2012, Vol. 29 ›› Issue (4): 564-571.

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Spectral Analysis and Structural Elucidation of Faropenem Sodium

 WANG Bin, JIA Zheng-Jun, JIANG Long, ZHANG Ming-Guang, WANG Ming-Lin, LIN Song, CHEN Zai-Xin*   

  1. R&D Center, Jiangsu Yabang Pharmaceutical Group, Changzhou 213200, China
  • Received:2011-11-29 Revised:2012-02-21 Online:2012-12-05 Published:2012-12-05
  • Contact: CHEN Zai-Xin, zaixin_chen@163.com E-mail:zaixin_chen@163.com

Abstract:

Faropenem sodium is a new and orally administered β-lactam antibiotic. The spectral data of faropenem sodium were reported, including UV, IR, MS, EA, TGA and NMR data. The NMR data included one-dimensional 1H  and 13C NMR spectra and two-dimensional spectra including 1H-1H COSY, HSQC and HMBC. The NMR and IR signals were assigned. The molecular structure of faropenem sodium was determined.

Key words: NMR, assignment, chemical shift, faropenem sodium, structural elucidation

CLC Number: