Chinese Journal of Magnetic Resonance ›› 2010, Vol. 27 ›› Issue (4): 617-622.

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An NMR Study on 2-[(2-Benzoxazolinone-3-yl)methyl]-6-phenyl-imidazo[2,1-b][1,3,4]thiadiazole

 LI Ying-Jun*, LI Chun-Yan, JIN Kun, AN Jing, WANG Lei-Lei, ZHAO Xing   

  1. College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China
  • Received:2010-01-18 Revised:2010-02-23 Online:2010-12-05 Published:2010-12-05
  • Supported by:

    Natural Science Foundation of Liaoning Province (20102126) and Education office Foundation of Liaoning Province (2008345)

Abstract:

Many compounds containing imidazo[2,1-b][1,3,4]thiadiazole ring showed pharmacological properties such as anticancer, antitubercular, antibacterial, antifungal, anticonvulsant, analgesic activities. In this paper, a novel compound which may have potential pharmaceutical applications, 2-[(2-benzoxazolinone-3-yl)methyl]-6-phenyl-imidazo[2,1-b][1,3,4] thiadiazole, was synthesized. Its 1H and 13C NMR chemical shifts were assigned using 2D NMR techniques, including gHMQC, gHMBC and 1H-1H COSY.

Key words: NMR, assignment, 2D NMR, 2-benzoxazolinone, imidazo[2,1-b][1,3,4]thiadiazole

CLC Number: