An NMR Study of Thymopoietin

Abstract

Abstract:

Severe spectral overlap occurs in the NMR spectrum of thymopoietin because the composing amino acid residuals have similar chemical shifts. In this paper, the structure of thymopoietin was determined by modified DPFGSE 1D-TOCSY and 1D-NOESY NMR techniques, which was then confirmed by computer simulation. The results demonstrate that DPFGSE 1D-TOCSY and 1D-NOE are efficient tools for structural elucidation of thymopoietin.

Key words: NMR, thymopoietin, structure, amino acid sequence, 1D-TOCSY, 1D-NOESY

CLC Number:

O641

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LIU Li-Jun, ZHONG Bo-Hua, MIAO Zhen-Chun. An NMR Study of Thymopoietin[J]. Chinese Journal of Magnetic Resonance, 2005, 22(2): 201-207.

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