ANALYSIS OF THE CONFIGURATION AND CONFORMATION OF GERMACRANE TYPE SESQUITERPENOIDS

Abstract

Abstract:

Germacrane type sesquiterpenoids are the most abundant among all the sesquiterpenoid skeletons. Their stereostructures vary much because of the decacycle. There are four configurational isomers and every configuration has several different conformers of germacrane derivatives, which tend to exist as the most stable conformers. All these conclusions are established by NMR spectroscopic techniques, including dynamics NMR (DNMR), NOED and NOESY, etc. These four configurational isomers and their relatively stable conformers are summarized by analyzing NMR spectral data in this article.

Key words: NMR, configuration, conformation, sesquiterpenoid, germacrane

CLC Number:

O641

GAO Kun, Li-Xin. ANALYSIS OF THE CONFIGURATION AND CONFORMATION OF GERMACRANE TYPE SESQUITERPENOIDS[J]. Chinese Journal of Magnetic Resonance, 2004, 21(2): 249-261.

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