Chinese Journal of Magnetic Resonance ›› 2017, Vol. 34 ›› Issue (4): 439-452.doi: 10.11938/cjmr20172562

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A Novel Method for Magnetic Resonance Ocular Imaging Using Super-Resolution Reconstruction

LI Yu-zhou1, ZHANG Zhe1, CHAN Kevin Chuen-wing2, GUO Hua1   

  1. 1. Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China;
    2. Departments of Ophthalmology and Radiology, NYU Langone Medical Center, New York University School of Medicine, New York 10016, United States
  • Received:2017-02-23 Revised:2017-10-23 Online:2017-12-05 Published:2017-11-29

Abstract: Magnetic resonance imaging (MRI) is a noninvasive intraocular tumor detection method without ionizing radiation. However, resolution limitation and motion artifacts are difficult to overcome in the imaging process. Conventional scanning methods inevitably introduce motion artifacts, or require the subjects to cooperate for accurate eye fixation, increasing the difficulty of imaging and giving the subject uncomfortable experiences. In this work, a new MRI method based on super-resolution theory is proposed, which uses a specialized orbit coil to scan a series of dynamic images of the eyeball, such that the acquisition resolution in different directions is complementary. High-resolution eyeball images with minimal motion artifacts could then be obtained after pre-processing, registration, super-resolution reconstruction and other operations. The study showed that the method proposed can be used to obtain clear eyeball images without the requirement of eye fixation.

Key words: magnetic resonance imaging (MRI), eyeball image, super-resolution, ocular imaging method

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