Synthesis and NMR Characterization of Ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate

Chinese Journal of Magnetic Resonance ›› 2007, Vol. 24 ›› Issue (2): 231-237.

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Synthesis and NMR Characterization of Ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate

LAI Yi-tian；ZHANG Xi-quan；LI Bao-lin；GUO jian；DOU Li-fang

School of Chemistry and Materials Science, Shaanxi Normal University, Xi’an 710062, China

Received:2006-09-11 Revised:2006-11-06 Online:2007-06-05 Published:2009-12-05
Contact: Li Bao-lin

Abstract

Abstract: A new compound ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate was synthesized from 3, 4-dimethoxybenzaldehyde and p-nitrotoluene via five steps, including condensation, catalytic reduction, diazotization, hydrolyzation and nucleophilic substitution. The structure of the compound was determined by 1D (¹H and ¹³C NMR) and 2D NMR techniques including ¹H-¹H COSY, HMQC and HMBC. All ¹H and ¹³C NMR chemical shifts of the compound were assigned.

Key words:

NMR, chemical shift assignment, ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate, p-nitrotoluene, 3, 4-dimethoxybenzaldehyde

LAI Yi-tian；ZHANG Xi-quan；LI Bao-lin；GUO jian；DOU Li-fang

. Synthesis and NMR Characterization of Ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate[J]. Chinese Journal of Magnetic Resonance, 2007, 24(2): 231-237.

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Synthesis and NMR Characterization of Ethyl 4-[(E)-2-(3, 4-dimethoxyphenyl)vinyl]phenoxyacetate

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