Chinese Journal of Magnetic Resonance ›› 2016, Vol. 33 ›› Issue (2): 353-359.doi: 10.11938/cjmr20160217

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An NMR Study on Lomustine

SUN Wei, GAO Xiang, GUO Juan, YU Xiang-yang   

  1. Key Laboratory of Synthetic and Natural Functional Molecular Chemistry, Ministry of Education, College of Chemistry & Material Science, Northwest University, Xi'an 710127, China
  • Received:2015-05-19 Revised:2016-04-15 Online:2016-06-05 Published:2016-06-05

Abstract:

Lomustine is an important drug having chiral carbon atoms. In the present study, one-dimensional 1H and 13C NMR, as well as two-dimensional techniques (i.e., 1H-13C HMBC, 1H-13C HSQC, 1H-1H COSY and 1H-1H NOESY) were used to elucidate the structure of Lomustine. The proton and carbon chemical shifts of the compound were assigned.

Key words: NMR, assignment, Lomustine

CLC Number: