Chinese Journal of Magnetic Resonance ›› 2020, Vol. 37 ›› Issue (2): 152-161.doi: 10.11938/cjmr20192717

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Prostate Cancer Diagnosis Based on Cascaded Convolutional Neural Networks

LIU Ke-wen1, LIU Zi-long1,2, WANG Xiang-yu3, CHEN Li2, LI Zhao2, WU Guang-yao4, LIU Chao-yang2   

  1. 1. School of Information Engineering, Wuhan University of Technology, Wuhan 430070, China;
    2. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan(Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences), Wuhan 430071, China;
    3. Department of Radiology, The First Affiliated Hospital of Shenzhen University, Shenzhen 518037, China;
    4. Department of Radiology, Shenzhen University General Hospital, Shenzhen 518055, China
  • Received:2019-02-28 Online:2020-06-05 Published:2019-05-30

Abstract: Interpreting magnetic resonance imaging (MRI) data by radiologists is time consuming and demands special expertise. Diagnosis of prostate cancer (PCa) with deep learning can also be time consuming and data storage consuming. This work presents an automated method for PCa detection based on cascaded convolutional neural network (CNN), including pre-network and post-network. The pre-network is based on a Faster-RCNN and trained with prostate images in order to separate the prostate from nearby tissues; the ResNet-based post-network is for PCa diagnosis, which is connected by bottlenecks and improved by applying batch normalization (BN) and global average pooling (GAP). The experimental results demonstrated that the cascaded CNN proposed had a good classification results on the in-house datasets, with less training time and computation resources.

Key words: magnetic resonance imaging (MRI), cascaded convolutional neural network (Cascaded CNN), prostate cancer (PCa), classification

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