波谱学杂志

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磁共振分子影像技术

雷皓   

  1. 中国科学院武汉物理与数学研究所,波谱与原子分子国家重点实验室,湖北武汉 430071
  • 收稿日期:2003-02-20 修回日期:2003-03-15 出版日期:2003-06-05 发布日期:2003-06-05
  • 作者简介:雷皓(1973-),男,湖南人,博士,研究员,从事生物医学磁共振成像和活体波谱的实验方法及应用研究.
  • 基金资助:

    中国科学院“引进海外杰出人才”计划; 国家自然科学基金重点项目(10234070).

MAGNETIC RESONANCE MOLECULAR IMAGING TECHNIQUES

LEI Hao   

  1. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics & Mathematics, The Chinese Academy of Sciences, Wuhan 430071, China
  • Received:2003-02-20 Revised:2003-03-15 Online:2003-06-05 Published:2003-06-05
  • Supported by:

    中国科学院“引进海外杰出人才”计划; 国家自然科学基金重点项目(10234070).

摘要:

磁共振分子影像技术是磁共振成像研究领域中最新的发展方向,它是利用磁共振成像为手段来无创伤地研究活体条件下生物细胞内的正常或病理状态下的分子过程的技术. 目前磁共振分子影像技术还处于其发展的初级阶段,但它在临床医学和基础研究中都具有非常广阔的应用前景,因而发展迅速. 文章综述了近几年来国际上磁共振分子影像技术的发展概况,并简要介绍了几类磁共振分子影像常用技术和其中所用到的分子探针.

关键词: 核磁共振, 分子影像, 磁共振成像, 分子探针

Abstract:

Magnetic resonance molecular imaging, which uses magnetic resonance imaging as a noninvasive tool to study in vivo cellular molecular events involved
in normal and pathologic processes, has recently become a hot topic in the research field of magnetic resonance imaging (MRI). Still in its early stage, the research on magnetic resonance molecular imaging has been growing rapidly due to the great values and potentials of the techniques in both clinical medicine and basic biomedical investigations. In this paper, the recent developments of magnetic resonance molecular imaging are reviewed. The methodological aspects of several types of  commonly used magnetic resonance molecular imaging techniques and the molecular probes used in the techniques are briefly introduced.

Key words: NMR, magnetic resonance imaging, MRI, molecular imaging, molecular probe

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