Acta mathematica scientia,Series B ›› 2011, Vol. 31 ›› Issue (5): 1959-1967.doi: 10.1016/S0252-9602(11)60374-3

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GLOBAL ASYMPTOTICAL PROPERTIES FOR A DIFFUSED HBV INFECTION MODEL WITH CTL IMMUNE RESPONSE AND#br# NONLINEAR INCIDENCE

 WANG Shao-Li1, FENG Xin-Long2, HE Yin-Nian1,2*   

  1. 1. Faculty of Science, Xi’an Jiaotong University, Xi’an 710049, China;
    2. College of Mathematics and Systems Science, Xinjiang University, Urumqi 830046, China
  • Received:2009-12-25 Revised:2010-05-06 Online:2011-09-20 Published:2011-09-20
  • Contact: HE Yin-Nian,heyn@mail.xjtu.edu.cn E-mail:wangshaoli110@163.com; fxlmath@gmail.com; heyn@mail.xjtu.edu.cn

Abstract:

This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equi-librium and immune-free equilibrium of the model are obtained. Global stability of the positive equilibrium of the model is also considered. The results show that the free diffu-sion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions.

Key words: HBV infection, diffusion, CTL immune response, nonlinear incidence, global asymptotical stability

CLC Number: 

  • 34D23
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