In this article, using generalized weighted mean and difference matrix of order m, we introduce the paranormed sequence space ?(u, v, p; Δ(m)), which consist of the sequences whose generalized weighted Δ(m)-difference means are in the linear space ?(p) defined by I.J.Maddox. Also, we determine the basis of this space and compute its α-, β- and γ-duals. Further, we give the characterization of the classes of matrix mappings from ?(u, v, p,Δ(m)) to ?∞, c, and c0. Finally, we apply the Hausdorff measure of noncompacness to characterize some classes of compact operators given by matrices on the space ?p(u, v, Δ(m)) (1≤p < 1).