The Alteration of Rich Club in Brain Functional Network in Internet Gaming Disorder

doi:10.11938/cjmr20212967

Abstract

Abstract:

Internet gaming disorder (IGD) has a great negative impact on teenagers’ study and life. It has been included in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders in 2013. However, the neural mechanism of its effect is yet to be unveiled. In this study, we used resting-state functional magnetic resonance imaging (resting-state fMRI) to explore the differences of rich club structures in the functional brain networks of 30 IGD subjects and 30 age/sex-matched healthy controls. The rich club was found in both IGD subjects and healthy controls, involving important brain regions in default mode, executive control, salience, sensorimotor, auditory and visual networks. IGD subjects had significantly higher rich club connection and higher degree in the right pars orbitalis of inferior frontal gyrus than healthy controls. These findings might suggest that IGD might be more correlated with damage to the rich club connection.

Key words: functional magnetic resonance imaging, brain functional network, rich club, internet gaming disorder

CLC Number:

O482.53

Xian-xin QIU,Xu HAN,Yao WANG,Wei-na DING,Ya-wen SUN,Yan ZHOU,Hao LEI,Fu-chun LIN. The Alteration of Rich Club in Brain Functional Network in Internet Gaming Disorder[J]. Chinese Journal of Magnetic Resonance, 2022, 39(3): 258-266.

Figures/Tables 6

Table 1

Fig.1

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Table 2

Table 3

Fig.3

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	IGD	HC	p值
年龄/岁	20.17±1.98	20.60±3.38	0.55
性别（女性/男性）	12/18	12/18	1.00
受教育年限/年	11.20±1.61	11.60±2.22	0.43
CIAS得分	73.10±10.21	39.83±8.81	<0.001
SAS得分	49.87±9.84	41.17±7.21	<0.001
SDS得分	53.27±9.91	44.57±9.77	0.001
BIS-11得分	61.07±8.76	53.40±7.67	0.001
认知冲动得分	15.03±2.76	12.93±2.50	0.003
行动冲动得分	20.33±4.06	17.97±3.12	0.014
非计划冲动得分	25.77±3.78	22.50±4.45	0.003

连接类型	连接				p值
连接类型	男性对照	男性IGD	女性对照	女性IGD	IGD	性别	IGD^*性别
rich club连接	16.26±2.71	17.76±2.65	17.52±3.59	19.59±4.89	0.01	0.57	0.44
feeder连接	98.98±10.13	99.02±15.34	94.33±18.60	102.04±13.37	0.82	0.97	0.16
local连接	245.9±20.99	239.09±17.09	232.08±16.75	241.82±17.02	0.82	0.25	0.04

连接类型		CIAS 得分	SAS 得分	SDS 得分	BIS-11 得分	BIS-11 -认知冲动得分	BIS-11 -行为冲动得分	BIS-11 -非计划冲动得分
rich club连接	r	?0.08	0.20	0.19	0.03	0.28	?0.15	0.00
rich club连接	p	0.69	0.32	0.35	0.90	0.17	0.48	0.99
feeder连接	r	0.05	0.09	0.15	?0.28	?0.05	?0.39	?0.19
feeder连接	p	0.82	0.66	0.47	0.17	0.80	0.05	0.35
local连接	r	0.42	0.24	0.35	0.03	?0.07	0.08	0.05
local连接	p	0.03	0.24	0.08	0.87	0.72	0.68	0.79

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