波谱学杂志 ›› 2006, Vol. 23 ›› Issue (3): 321-326.

• 研究论文 • 上一篇    下一篇

人参茎叶中一个新天然产物的结构研究

王立波,高慧媛,吴斌,宋小妹,唐志书,王薇,吴立军   

  1. 1.沈阳药科大学中药学院,辽宁 沈阳 110016; 2.陕西中医药大学, 陕西 咸阳712046
  • 收稿日期:2005-11-16 修回日期:2006-01-09 出版日期:2006-09-05 发布日期:2009-12-05
  • 通讯作者: 吴立军

Structure Determination of A Novel Natural Product Isolated from the Leaves of Panax Ginseng CA Meyer

WANG Li-bo, GAO Hui-yuan, WU Bin, SONG Xiao-mei, TANG Zhi-shu, WANG Wei, WU Li-jun   

  1. 1.School of Traditional Chinese Medical, Shenyang Pharmaceutical University, Shenyang 110016, China; 2.School of Shanxi University of Chinese Medicine, Xianyang 712046, China
  • Received:2005-11-16 Revised:2006-01-09 Online:2006-09-05 Published:2009-12-05
  • Contact: WU Li-jun

摘要: 采用多种色谱方法从人参茎叶中分离得到一个新天然产物-达玛烷型三萜皂苷元dammar20(22), 24-diene-3β,6α,12β-triol,并利用质谱、核磁共振谱和化学方法对此化合物进行了结构解析. 通过2D NMR(HMQC、HMBC)进行了1H和13C NMR信号全归属,并纠正了文献中的个别化学位移的信号指认错误.

关键词: 核磁共振, 人参, NMR全归属

Abstract: A novel natural product was isolated from the leaves of Panax ginseng CA Meyer by column chromatography. Using mass spectrometry, NMR spectroscopy and conventional chemical methods, the chemical structure of the compound was determined to be dammar-20(22), 24-diene-3β, 6α, 12βtriol. Complete assignment of 1H and 13C chemical shifts of this compound was obtained, and the results pointed out an error existed in the previous assignment.

Key words: NMR, Panax ginseng CA Meyer, chemical shift assignment

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