波谱学杂志 ›› 2004, Vol. 21 ›› Issue (2): 221-229.

• 研究论文 • 上一篇    下一篇

3种药物分子的1H和13C NMR谱线全指定

李勤1, 杨春晖1,刘雪辉1,赵兴凯2,崔育新1*   

  1. 1.北京大学 天然药物及仿生药物国家重点实验室,医药卫生分析中心,北京 100083;
    2.北京天衡药物研究院,北京 100071
  • 收稿日期:2003-10-13 修回日期:2003-11-07 出版日期:2004-06-05 发布日期:2004-06-05

1H AND 13C NMR CHEMICAL SHIFT ASSIGNMENT FOR THREE DRUGS

 LI Qin1, YANG Chun-Hui1, LIU Xue-Hui1, ZHAO Xing-Kai2, CUI Yu-Xin1*   

  1. 1.National Research Laboratory of Natural and Biomimetic Drugs, Medical and Healthy Analysis Center, Peking University, Beijing 100083, China;
    2.Team Academy of Pharmaceutical Science, Beijing 100071, China
  • Received:2003-10-13 Revised:2003-11-07 Online:2004-06-05 Published:2004-06-05

摘要:

应用1D和2D NMR技术,对3种药物分子:比卡鲁胺(Bicalutamide)、马来酸罗格列酮(Rosiglitazone Maleate)、氯吡格雷硫酸盐(Clopidogrel Hydrogensulfate)的1H和13C NMR的谱峰进行了准确归属.

关键词: 核磁共振, 归属, 比卡鲁胺, 马来酸罗格列酮, 氯吡格雷

Abstract:

The structures of bicalutamide, rosiglitazone maleate, clopidogrel hyd rogensulfate were elucidated by 1D and 2D NMR spectroscopy. The  1H and 13C NMR chemical shifts of these compounds were assigned.

Key words: NMR, assigaments, bicalutamide, rosiglitazone maleate, clopidogrel hydrogensulfate

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