永磁微型磁共振成像仪的梯度线圈与图像质量

波谱学杂志 ›› 2012, Vol. 29 ›› Issue (4): 508-520.

• 磁共振谱仪研制技术进展专栏 • 上一篇下一篇

永磁微型磁共振成像仪的梯度线圈与图像质量

侯淑莲^1*, 谢寰彤², 侯晓吻³, 李石玉¹, 陈伟¹

1. 河北联合大学基础医学院, 河北唐山 063000; 2.上海寰彤科教设备有限公司, 上海 201806;
3. 杭州电子科技大学, 浙江杭州 310000

收稿日期:2011-11-18 修回日期:2012-05-08 出版日期:2012-12-05 发布日期:2012-12-05
基金资助:
河北省科学技术厅科研计划资助项目（08202133D）.

Gradient Coil of Permanent Magnet Mini-Magnetic Resonance Imager and Image Quality

HOU Shu-Lian^1*, XIE Huan-Tong², HOU Xiao-Wen³, LI Shi-Yu¹, CHEN Wei¹

1. College of Elementary Medicine, Hebei United University, Tangshan 063000, China;
2. Shanghai HuanTong Science and Education Equipment Co., LTD, Shanghai 201806, China;
3. Hangzhou Dianzi University, Hangzhou 310000, China

Received:2011-11-18 Revised:2012-05-08 Online:2012-12-05 Published:2012-12-05
Supported by:
河北省科学技术厅科研计划资助项目（08202133D）.

摘要/Abstract

摘要：

通过理论分析结合计算机仿真试验剖析了磁共振成像(MRI)中梯度场线性对图像质量影响的原理，在梯度场线性有缺陷的情况下，用实例和计算机模拟直观的展示了重建图像和模拟结果. 结合研发实践发现，在永磁微小口径、低场强用于鼠类等小动物成像情况下，对梯度场线性度的要求远高于文献中提出的指标. 依靠软件改进，图像没有本质的提高，尝试补偿技术耗时费力效果也不理想. 说明了对永磁微小口径成像仪研发线性度更好的梯度线圈是提高图像质量的关键技术之一. 揭示了在理想条件下普适的理论原理，在不同的实践条件下有不同的趋近理想条件要求. 将具有独立知识产权的高线性梯度线圈安装在自行研制的仪器上得到了较好的图像.

关键词: 磁共振成像(MRI), 永磁微型三维磁共振成像仪, 线性, 梯度线圈, 计算机仿真

Abstract:

Effects of gradient field linearity on the quality of images acquired on a permanent magnet mini-magnetic resonance imager were analyzed by theoretical analyses and numerical simulation. It was shown that gradient field with high linearity is a prerequisite to obtain high-quality images of small animals, such as mice, on permanent magnet, low field strength micro-magnetic resonance imagers. The gradient field linearity specification reported in the literature is too low to acquired high-quality mouse images. The image quality could not be improved by software compensation methods. The newly developed gradient field coil with high linear property and our independent intellectual property was also presented. The optimized gradient coil has been installed on our instrument, and yielded a better quality image.

Key words: MRI, Permanent Magnet Mini-mgnetic 3D Resonance Imager, linearity, gradient coil, simulation

中图分类号:

R318.6
R332

侯淑莲, 谢寰彤, 侯晓吻, 李石玉, 陈伟. 永磁微型磁共振成像仪的梯度线圈与图像质量[J]. 波谱学杂志, 2012, 29(4): 508-520.

HOU Shu-Lian, XIE Huan-Tong, HOU Xiao-Wen, LI Shi-Yu, CHEN Wei. Gradient Coil of Permanent Magnet Mini-Magnetic Resonance Imager and Image Quality[J]. Chinese Journal of Magnetic Resonance, 2012, 29(4): 508-520.

参考文献

[1] Barry L W. Gradients: The heart of the MRI machine[J]. Curr Med Imaging Reviews, 2006, 2(1): 131-138.

[2] Gary H, Norbert J. Method for correcting image distortion due to gradient nonuniformity: US, 4591789[P]. 1986-5-27.

[3] Michiels J, Bosmans H, Pelgrims P, et al. On the problem of geometric distortion in magnetic resonance images for stereotactic neurosurgery[J]. Magn Reson Imaging. 1994, 12(5): 749-765.

[4] Walton L, Hampshire A, Forster D M, et al. A phantom study to assess the accuracy of stereotactic localization, using T1 weighted magnetic resonance imaging with the Leskell stereotactic system[J]. Neurosurgery, 1996, 38(1): 170-178．

[5] Xu Qin(徐勤), Wang He(王鹤), Jiang Yu(蒋瑜), et al. A digital preemphasis gradient waveform generator for magnetic resonance imaging (一种具有数字预加重的磁共振成像梯度波形发生器)[J]．Chinese J Magn Reson (波谱学杂志), 2006, 23(1): 11-16.

[6] Sanchez H , Liu F, Trakic A, et al. Three-dimensional gradient coil structures for magnetic resonance imaging designed using fuzzy membership functions[J]. IEEE T Magn, 2007, 43(9): 3 558-3 566.

[7] Zang Feng-chao(臧凤超), Li Jian-qi(李建奇), Wang He(王鹤), et al. Automatic adjustment of gradient preemphasis in MRI systems (磁共振成像系统中的自动梯度预加重调节方法研究) [J]. Chinese J Magn Reson (波谱学杂志), 2008, 25(1): 26-32.

[8] Connell, M A, Bowyer P J, Bone P, et al. Improving the accuracy of pulsed field gradient NMR diffusion experiments: Correction for gradient non-uniformity[J]. J Magn Reson, 2009, 198(1): 121-131.

[9] Xiao Liang(肖亮)，Tang Wei-nan(汤伟男)，Wang Wei-min(王为民).An FPGA-based single-chip gradient calculation module for magnetic resonance imaging (基于FPGA的磁共振成像梯度计算模块)[J]．Chinese J Magn Reson(波谱学杂志), 2010, 27(2): 163-171.

[10] While P T, Forbes L K, Crozier S. Designing gradient coils with reduced hotspot temperatures[J]. J Magn Reson, 2010, 203(1): 91-99.

[11] Zu Dong-lin(俎栋林)，Magnetic Resonance Imaging Study（核磁共振成像学）[M]. Beijing (北京)：Higher Education Press (高等教育出版社), 2004.

[12] Haacke M E, Brown R W, Thompson M R, et al. Magnetic resonance imaging: phsical principles and sequence design[M]. New York: Wiley-Liss, 1999.

[13] Hashemi R H, Bradley W G, Lisanti C J. MRI: The Basics (2nd ed)[M]. Philadelphia: Lippincott Williams & Wilkins, 2004.

[14] Lai C M. Reconstructing NMR images under nonlinear field gradients[J]. Phys E: Sci Instrum, 1983, 16: 34-38. 

[15] 谢寰彤.核磁共振磁体设备, 中国: 01276446[P]. 2002-10-23. 

[16] Tao Yue-hui (陶岳辉). New algorithm of MRI gradient correction. (磁共振成像梯度校正的新方法)[D]．Shanghai(上海)：Fundan University(复旦大学), 2003.

永磁微型磁共振成像仪的梯度线圈与图像质量

Gradient Coil of Permanent Magnet Mini-Magnetic Resonance Imager and Image Quality

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