电子自旋共振(ESR)技术在生物和医学中的应用

摘要/Abstract

摘要：

电子自旋共振(electron spin resonance，ESR)是检测自由基最直接最有效的方法，是自由基生物学和医学不可缺少的重要研究技术. 作者综述了ESR、自旋标记、自旋捕集和ESR 成像技术的最新发展及ESR技术在细胞膜、蛋白质结构和一些重大疾病如心脏病、老年痴呆症、帕金森综合症和中风等疾病研究及辐射损伤和植物疾病研究中的应用.

关键词: 电子自旋共振(ESR), 自旋标记, 自旋捕集, ESR成像技术, 生物, 医学

Abstract:

Electron spin resonance (ESR) is the most direct technique and an effective and unique way to detect free radicals in biological samples. This paper reviews the applications of ESR in biology and medicine. The topics reviewed include development of spin labeling and spin trapping, ESR imaging and applications of ESR in studies of cell membrane, protein structure, and diseases (i.e., heart diseases, Alzheimer's disease, Parkinson’s disease, stoke, radiation damage and plant diseases).

Key words: ESR, spin labeling, spin trapping, ESR imaging, biology, medicine

中图分类号:

O482.53

赵保路. 电子自旋共振(ESR)技术在生物和医学中的应用[J]. 波谱学杂志, 2010, 27(1): 51-67.

ZHAO Bao-Lu. Applications of Electron Spin Resonance in Biology and Medicine[J]. Chinese Journal of Magnetic Resonance, 2010, 27(1): 51-67.

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