波谱学杂志 ›› 1993, Vol. 10 ›› Issue (1): 61-67.

• 研究论文 • 上一篇    下一篇

赤霉酸甲酯及其类似物的2D NMR研究

崔育新, 李宇, 谢文革, 潘鑫复   

  1. 兰州大学应用有机化学国家重点实验室, 兰州大学应用有机化学国家重点实验室, 兰州 730000
  • 收稿日期:1992-05-16 修回日期:1992-10-13 出版日期:1993-03-05 发布日期:2018-01-20

2D NMR STUDIES ON METHYL GIBBERELLATE AND ITS ANALOGUES

Cui Yuxin, Li Yu, Xie Wenge, Pan Xinfu   

  1. The State Key Laboratory of Applied Organic Chemistry Lanzhou University, The Institute of Organic Chemistry Lanzhou University, Lanzhou 730000
  • Received:1992-05-16 Revised:1992-10-13 Online:1993-03-05 Published:2018-01-20

摘要: 应用1H-1H COSY,NOESY,13C-1H COSY等2DNMR和DEPT技术,完成了赤霉酸甲酯(2),13-O-乙酰基赤霉素甲酯(3)及其3位差向异构体(4)的1H和13CNMR化学位移的全指定,并探讨了它们的相对构型,相关质子间的偶合常数也支持所得结果。

关键词: 2D NMR, 化学位移, 赤霉酸甲酯, 差向异构体, 构型

Abstract: Gibberellins form an important group of plant growth hormone, which have many biological activities. Its structure was determined by X-ray single crystal diffraction, no complete assignment of 1H and 13C NMR spectrum of the compounds have been reported. In this paper, all the 1H and 13C NMR chemical shifts of methyl gibberellate (2), 13-acetoxygibberellin A1 methyl ester (3) and its 3-epimer (4) were assigned by 1H-1H COSY, 13C-1H COSY, NOESY and DEPT, and their relative configurations were discussed.

Key words: Two-dimensional NMR, Chemical shift, Methyl gibbercllate, Epimer, Configuration