关键词: 核磁共振, 超低温探头, 综述, 天然产物, 生物大分子

Abstract:

Bruker´s CryoProbes^TM show large improvement in terms of NMR detection sensitivity over the last few decades. This paper provides a detailed review on the technical innovation and applications of various Bruker CryoProbes^TM. The large increase of detection sensitivity of CryoProbes^TM enables experiments on samples with amounts that were considered too small just a few years ago to have reliable results. With the CryoProbes^TM, sample throughput can also be increased up to 16-fold. With the increasing variety of CryoProbe models, the applications of Cryoprobes^TM will expand further into other new fields.

Key words: NMR, CryoProbe^TM, overview, natural product, biological macromolecule