波谱学杂志 ›› 2012, Vol. 29 ›› Issue (4): 489-498.

• 磁共振谱仪研制技术进展专栏 • 上一篇    下一篇

一体化NMR波谱仪梯度场频联锁匀场系统设计

王恢旺,李正刚,毛文平,鲍庆嘉,刘造,刘朝阳   

  1. 1. 波谱与原子分子物理国家重点实验室,武汉磁共振中心(中国科学院 武汉物理与数学研究所),湖北 武汉 430071;  
    2. 中国科学院大学,北京 100049; 
    3. 华中科技大学,湖北 武汉 430074
  • 收稿日期:2012-02-22 修回日期:2012-04-13 出版日期:2012-12-05 发布日期:2012-12-05
  • 基金资助:

    国家自然科学基金资助项目(10675162),国家重大科学仪器设备开发专项资助项目(2011YQ120035),科技支撑计划资助项目(2006BAK03A22).

The Design of An Integrated Gradient Field/Frequency Lock Shim System for NMR Spectrometer

WANG Hui-Wang, LI Zheng-Gang, MAO Wen-Ping, BAO Qiang-Jia, LIU Zao, LIU Chao-Yang   

  1. 1. State Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, Wuhan Center for Magnetic Resonance (Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences), Wuhan 430071, China;
    2. University of Chinese Academy of Sciences, Beijing 100049, China;
    3. Huazhong University of Science and Technology, Wuhan 430074, China
  • Received:2012-02-22 Revised:2012-04-13 Online:2012-12-05 Published:2012-12-05
  • Supported by:

    国家自然科学基金资助项目(10675162),国家重大科学仪器设备开发专项资助项目(2011YQ120035),科技支撑计划资助项目(2006BAK03A22).

摘要:

介绍一体化核磁共振波谱仪梯度-场频联锁-匀场系统的设计方案. 该方案使用嵌入式以太网、FPGA(Field Programmable Gate Array,现场可编程门阵列)、EMI(External Memory Interface, 外部存储器接口)和高速串行总线等技术构建了基于以太网的通信系统和使用并行运算的控制系统, 并具备CAN(Controller Area Network,控制器局域网)总线通信的能力. 梯度放大器通过LVDS(Low-Voltage Differential Signaling,低压差分信号传输)接口与主控系统的梯度波形发生器连接,实现与谱仪工作站的交互. 系统采用插板式结构和通用性电路的设计方法,具有很好的扩展能力和适应性,能够满足不同谱仪的需求. 系统在11.7 T(500 MHz)NMR系统中进行了有效的锁场、匀场和梯度特性的测试,证明了该方案的可行性.

关键词: 核磁共振(NMR),  , 梯度,  , 场频联锁,  , 匀场,  , 一体化

Abstract:

The design of an integrated gradient-field/frequency lock-shim system for NMR spectrometer is presented. The integrated architecture is realized by combining embedded ethernet, field programmable gate array (FPGA), external memory interface (EMI), controller area network (CAN) bus and high-speed serial bus technologies, making the system compact and reliable. The system consists of three parts: (1) the field/frequency lock subsystem which ensures the stability of the magnetic field, (2) the shim subsystem which guarantees the consistency of the magnetic field, and (3) the gradient amplifier which generates the gradient field pulse. Due to its flexibility, the design can easily be adapted for different NMR spectrometers. The feasibility of the integrated system is illustrated by  tests of the shim, lock and gradient outputs on a 11.7 T NMR spectrometer.

Key words: NMR, gradient, field/frequency lock, shim, integration

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