波谱学杂志 ›› 2010, Vol. 27 ›› Issue (1): 95-102.

• 恭祝徐广智先生八十华诞(专辑) • 上一篇    下一篇

一种新型功能化双自由基的合成及EPR表征

  

  1. Center for Biomedical EPR Spectroscopy and Imaging, The Davis Heart and Lung Research Institute, The Division of Cardiovascular Medicine, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
  • 收稿日期:2009-12-15 出版日期:2010-03-05 发布日期:2010-03-05
  • 基金资助:

    National Institutes of Health grants (HL38324, EB0890 and EB4900).

Synthesis and EPR Characterization of a Novel Functional Biradical

  1. Center for Biomedical EPR Spectroscopy and Imaging, The Davis Heart and Lung Research Institute, The Division of Cardiovascular Medicine, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
  • Received:2009-12-15 Online:2010-03-05 Published:2010-03-05
  • Supported by:

    National Institutes of Health grants (HL38324, EB0890 and EB4900).

摘要:

新开发的双自由基 (TN3) 由全取代三苯甲基自由基 (trityl)和氮氧自由基两部分组成. TN3的室温EPR谱图由4条不对称的宽谱线组成, 具有典型的双自由基特征. 以抗坏血酸作为模型化合物发现该双自由基能用来同时检测体系的氧化还原态和氧气浓度.

关键词: 氮氧自由基, 氧化还原态, 氧气, 电子顺磁共振(EPR), 双自由基, 三苯甲基自由基

Abstract:

A biradical TN3 was synthesized, which is composed of a fully substituted triphenylmethyl radical and a nitroxide. EPR spectrum of TN3 at room temperature  consists of an asymmetric quartet broad lines, suggesting its typical biradical structure. Using- ascorbate as a model compound, we proved that TN3 can be used to evaluate redox status and oxygen level simultaneously.

Key words: EPR,  biradical, trityl, nitroxide,  redox status, oxygen

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