高场磁共振成像1H/31P双调谐射频线圈研究进展

doi:10.11938/cjmr20202826

摘要/Abstract

摘要： 在众多可产生磁共振现象的原子核中，¹H核凭借其在生物体中含量高、磁共振信号强的优势，成为磁共振成像的主要研究对象．但其它杂核在生命科学相关研究中同样具有不可替代的独特性，如³¹P核广泛参与了生物体内的能量代谢过程，是非质子成像研究领域的重要内容．MRI向更高场强的发展使得杂核成像逐渐普及，其核心部件是高质量的¹H/³¹P双调谐射频线圈．本文总结了与¹H/³¹P双调谐射频线圈相关的研究与应用，展示了9.4 T下小鼠脑的质子磁共振成像及磁共振磷谱，并讨论了高场¹H/³¹P双调谐射频线圈的潜在应用价值．

关键词: 高场磁共振成像, 射频线圈, ¹H, ³¹P, 双调谐

Abstract: ¹H nucleus is the most commonly used nucleus for magnetic resonance imaging (MRI) due to its high natural abundance in organisms and high MR sensitivity. However, other nuclei are distinctive in physiological processes, such as ³¹P that is important in the energy metabolisms. The development of high-field MRI allows for MRI research based on ³¹P nucleus, while high-quality ¹H/³¹P dual-tuned radio frequency (RF) coil is essential for such applications. This article summarized the researches and applications of various ¹H/³¹P dual-tuned RF coils, and presented in vivo ¹H MRI and ³¹P MR spectra of mouse brain at 9.4 T. Potential applications of ¹H/³¹P dual-tuned RF coil for high field were discussed.

Key words: high-field magnetic resonance imaging, radio frequency coil, ¹H, ³¹P, dual-tuned

中图分类号:

O482.53

马聪伟, 杨鸿毅, 钟凯. 高场磁共振成像¹H/³¹P双调谐射频线圈研究进展[J]. 波谱学杂志, 2021, 38(1): 118-139.

MA Cong-wei, YANG Hong-yi, ZHONG Kai. Research Progresses of High-Field MRI ¹H/³¹P Dual-Tuned Radio Frequency Coil[J]. Chinese Journal of Magnetic Resonance, 2021, 38(1): 118-139.

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高场磁共振成像¹H/³¹P双调谐射频线圈研究进展

Research Progresses of High-Field MRI ¹H/³¹P Dual-Tuned Radio Frequency Coil

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