An NMR Study of Two Lignans Isolated from Schisandra Chinensis

Abstract

Abstract:

Three lignans were isolated from the fruits of Schisandra chinensis bail, and identified as mesodihydroguaiaretic acid(Ⅰ), Gomisin J(Ⅱ) and Gomisin D(Ⅲ) using 1D and 2D NMR techniques. Complete assignment of NMR signals was obtained for compounds Ⅱand Ⅲ. The stereo configuration of Gomisin D was simulated by three molecular simulation methods using the SYBYL software, and the most stable configuration of Gomisin D was calculated.

Key words: 2D NMR, Schisandra chinensis, Gomisin J, Gomisin D, computer molecular simulation

CLC Number:

O641

CHEN Hai-Yong, ZHOU Chang-Xin, YAO Wei, WANG Li-Wei, DOU Hui, DONG Xiao-Wu, ZHAO Yu. An NMR Study of Two Lignans Isolated from Schisandra Chinensis[J]. Chinese Journal of Magnetic Resonance, 2005, 22(1): 43-54.

References

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