Chinese Journal of Magnetic Resonance ›› 2005, Vol. 22 ›› Issue (1): 55-60.

• Articles • Previous Articles     Next Articles

Structural Confirmation of a Derivative of 6, 7; 12, 21-Didehydroerythromycin A  by 13C NMR DEPT Technique

  

  1. Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • Received:2004-09-14 Revised:2004-10-25 Online:2005-03-05 Published:2005-03-05

Abstract:

The derivatives of (9S)-12-methyleneerythromycin A,  compound (5) and (6),  were obtained by elimination reaction between thionyl chloride and corresponding 2′-O,  4″-O-dibenzoyl-(9S)-9-O, 11-O-isopropylerythromycin A. The structure of (6) was established using 13C NMRDEPT spectroscopy.

Key words: 13C NMR, DEPT, 6, 7;12, 21-didehydroerythromycin A, elimination

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