Gaining Higher NMR Signal Enhancement with Parahydrogen-Induced Polarization

doi:10.11938/cjmr20150308

Abstract

Abstract:

Parahydrogen-induced polarization (PHIP) can enhance NMR signals significantly, and thus has shown great prospects in chemistry, biology, medical science and so on. In practice, the amplitude of NMR signal enhancement by PHIP, however, is often limited by experiment setup. In this work, it was demonstrated the signal enhancement in PHIP experiments can be optimized by choosing appropriate experimental conditions, including temperature, pressure and the way to introduce parahydrogen into the PHIP experiment. The reaction system of 1-hexyne and [Rh(COD)(dppb)]BF₄ was chosen as the example to illustrate how to optimize experimental conditions in PHIP experiments.

Key words: parahydrogen induced polarization (PHIP), PASADENA, ALTADENA, solution NMR, hydrogenation reaction

CLC Number:

O482.53

SONG Yan-hong，LIU Wen-qing，YAO Ye-feng*. Gaining Higher NMR Signal Enhancement with Parahydrogen-Induced Polarization[J]. Chinese Journal of Magnetic Resonance, 2015, 32(3): 470-480.

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