[1] Alberti K, Zimmet P, Shaw J. A consensus statement from the International Diabetes Federation[J]. Diabet Med, 2010, 23(5): 469-480. [2] Brownlee M. Biochemistry and molecular cell biology of diabetic complications[J]. Nature, 2001, 414(6 865): 813-820. [3] Reske-Nielsen E, Lundbaek K. Pathological changes in the central and peripheral nervous system of young long-term diabetics. II. The spinal cord and peripheral nerves[J]. Diabetologia, 1968, 4(1): 34-43. [4] Di Marzio D, Mohn A, Mokini Z H, et al. Macroangiopathy in adults and children with diabetes: from molecular mechanisms to vascular damage (part 1)[J]. Horm Metab Res, 2006, 38(11): 691-705. [5] Folli F, Guzzi V, Perego L, et al. Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients’ skin which are normalized by kidney-pancreas transplantation[J]. PLoS One, 2010, 5(3): e9923. [6] Rask-Madsen C, King G L. Mechanisms of disease: endothelial dysfunction in insulin resistance and diabetes[J]. Nat Clin Pract Endocrinol Metab, 2007, 3(1): 46-56. [7] Vlassara H, Brownlee M, Cerami A. Excessive nonenzymatic glycosylation of peripheral and central nervous system myelin components in diabetic rats[J]. Diabetes, 1983, 32(7): 670-674. [8] Auer R N, Siesjö B K. Biological differences between ischemia, hypoglycemia, and epilepsy[J]. Ann Neurol, 1988, 24(6): 699-707. [9] Auer R N, Olsson Y, Siesjö B K. Hypoglycemic brain injury in the rat. Correlation of density of brain damage with the EEG isoelectric time: a quantitative study[J]. Diabetes, 1984, 33(11): 1 090-1 098. [10] Auer R N, Hugh J, Cosgrove E, et al. Neuropathologic ?ndings in three cases of profound hypoglycemia[J]. Clin Neuropathol, 1989, 8(2): 63-68. [11] Fujioka M, Okuchi K, Hiramatsu K I, et al. Speci?c changes in human brain after hypoglycemic injury[J]. Stroke, 1997, 28(3): 584-587. [12] Kalimo H, Olsson Y. Effects of severe hypoglycemia on the human brain. Neuropathological case reports[J]. Acta Neurol Scand, 1980, 62(6): 345-356. [13] Sieber F E, Traystman R J. Special issues: glucose and the brain[J]. Crit Care Med, 1992, 20(1): 104-114. [14] McCall A L. The impact of diabetes on the CNS[J]. Diabetes, 1992, 41(5): 557-570. [15] Wieloch T. Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist[J]. Science, 1985, 230(4 726): 681-683. [16] Ouyang Y B, He Q P, Li P A, et al. Is neuronal injury caused by hypoglycemic coma of the necrotic or apoptotic type[J]. Neurochem Res, 2000, 25(5): 661-667. [17] Xu Wen-xin(徐雯欣), An Yan-peng(安艳捧), Tang Hui-ru(唐慧儒). NMR studies of Streptozotocin effects on rat plasma fatty acids(链脲佐菌素影响大鼠脂肪酸代谢的NMR研究)[J]. Chinese J Magn Reson(波谱学杂志) , 2013, 30(2): 204-212. [18] Huang Ming-ming(黄明明), Lin Fu-chun(林富春), Gao Li-feng(高丽凤), et al. Diabetic encephalopathy studied by magnetic resonance imaging and spectroscopy(糖尿病脑病的磁共振研究)[J]. Chinese J Magn Reson(波谱学杂志) , 2012, 29(3): 446-456. [19] Tiehuis A M, van der Graaf Y, Visseren F L, et al. Diabetes increases atrophy and vascular lesions on brain MRI in patients with symptomatic arterial disease[J]. Stroke, 2008, 39(5): 1 600-1 603. [20] Ferguson S C, Blane A, Wardlaw J, et al. Influence of an early-onset age of type 1 diabetes on cerebral structure and cognitive function[J]. Diabetes Care, 2005, 28(6): 1 431-1 437. [21] Pell G S, Lin A, Wellard R M, et al. Age-related loss of brain volume and T2 relaxation time in youth with type 1 diabetes[J]. Diabetes Care, 2012, 35(3): 513-519. [22] Brands A M, Kessels R P, Hoogma R P, et al. Cognitive performance, psychological well-being, and brain magnetic resonance imaging in older patients with type 1 diabetes[J]. Diabetes, 2006, 55(6): 1 800-1 806. [23] Falvey C M, Rosano C, Simonsick E M, et al. Macro- and micro-structural magnetic resonance imaging indices associated with diabetes among community-dwelling older adults[J]. Diabetes Care, 2013, 36(3): 677-682. [24] Musen G, Lyoo I K, Sparks C R, et al. Effects of type 1 diabetes on gray matter density as measured by voxel-based morphometry[J]. Diabetes, 2006, 55(2): 326-333. [25] Schweinhardt P, Bushnell M C. Pain imaging in health and disease—how far have we come[J]. J Clin Invest, 2010, 120(11): 3 788-3 797. [26] Scoville W B, Milner B. Loss of recent memory after bilateral hippocampal lesion[J]. J Neurol Neurosurg Psychiatry, 1957, 20(1): 11-21. [27] Zola-Morgan S M, Sguire L R. The primate hippocampal formation: evidence for a time-limited role in memory storage[J]. Science, 1990, 250(4 978): 288-290. [28] Gaudieri P A, Chen R, Greer T F, et al. Cognitive function in children with type 1 diabetes: a meta-analysis[J]. Diabetes Care, 2008, 31(9): 1 892-1 897. |