基于分子间多量子相干的矢量场磁共振成像模拟

波谱学杂志 ›› 2007, Vol. 24 ›› Issue (4): 394-400.

• 祝贺邬学文先生八十华诞（专辑） • 上一篇下一篇

基于分子间多量子相干的矢量场磁共振成像模拟

蔡聪波¹, 蔡淑惠², 董继扬^2, 陈忠^2*

1.厦门大学通信工程系，福建厦门 361005; 2.厦门大学物理系，福建厦门 361005

收稿日期:2007-08-28 出版日期:2007-12-05 发布日期:2007-12-05
作者简介:蔡聪波(1975-),男，福建泉州人，博士，讲师,从事核磁共振研究.*通讯联系人：陈忠，电话：0592-2181712，E-mail:chenz@xmu.edu.cn.
基金资助:
国家自然科学基金(10605019)和福建省自然科学基金(T0750015)资助项目.

Simulation of Vector Field Magnetic Resonance Imaging Based on Inter-Molecular Multiple-Quantum Coherences

CAI Cong-bo¹, CAI Shu-hui², DONG Ji-yang², CHEN Zhong^2*

1.Department of Communications Engineering, Xiamen University, Xiamen 361005, China; 
2.Department of Physics, Xiamen University, Xiamen 361005, China

Received:2007-08-28 Online:2007-12-05 Published:2007-12-05
About author:*Corresponding author: Chen Zhong, Tel: 05922181712, Email: chenz@xmu.edu.cn.
Supported by:
国家自然科学基金(10605019)和福建省自然科学基金(T0750015)资助项目.

摘要/Abstract

摘要：

对基于分子间多量子相干的矢量场成像进行了系统的模拟研究. 模拟结果表明：这类成像能够对几十微米量级的异质结构进行成像，并较好地抑制来自均匀介质的信号. 即使不存在梯度磁场情况下，通过相位循环该方法亦可实现对异质结构的成像. 这将有助于开拓基于分子间多量子相干成像的应用领域，深化对其成像机制的理解.

关键词: 分子间多量子相干, 矢量场, 成像, 模拟

Abstract:

In this paper, a comprehensive simulation of the vector field imaging based on the inter-molecular multiple quantum coherences (iMQC) was performed. The results showed that this imaging technique can be applied to image heterogeneities on the scale of dozens of micrometers, with adequate suppression of the signals from homogeneous medium. It was shown that imaging of field heterogeneities can also be achieved through phase cycling even without correlation gradients. These results would be of great help in extending the applications of iMQC imaging and in further understanding the mechanism underlying iMQC imaging.

Key words: iMQC, vector field, MRI, simulation

中图分类号:

O482.53

蔡聪波1, 蔡淑惠2, 董继扬2, 陈忠2*. 基于分子间多量子相干的矢量场磁共振成像模拟[J]. 波谱学杂志, 2007, 24(4): 394-400.

CAI Cong-bo1, CAI Shu-hui2, DONG Ji-yang2, CHEN Zhong2*. Simulation of Vector Field Magnetic Resonance Imaging Based on Inter-Molecular Multiple-Quantum Coherences[J]. Chinese Journal of Magnetic Resonance, 2007, 24(4): 394-400.

参考文献

[1] Lauterbur P C. Image formation by induced local interaction: Examples employing nuclear magnetic resonance[J]. Nature, 1973, 242: 190-191. 

[2] Alper J. Biomedicine in the age of imaging[J]. Science, 1993, 261: 554-561.

[3] Caravan P, Ellison J J, McMurry T J, et al. Gadolinium(Ⅲ) chelates as MRI contrast agents: Structure, dynamics, and applications[J]. Chem Rev, 1999, 99: 2 293-2 352.

[4] Edelman R R, Zlatkin M B, Hesselik J R, ed. Clinical Magnetic Resonance Imaging (2nd ed)[M]. Philadelphia: Saunders, 1996. 177.

[5] Louis S. B, Warren W S. Multiple-quantum vector field imaging by magnetic resonance[J]. J Magn Reson, 2005, 177: 9-21.

[6] Bowtell R, Robyr P. Structural investigations with the dipolar demagnetizing field in solution NMR, Phys Rev Lett, 1996, 76: 4 971-4 974.

[7] Warren W S, Ahn S, Mescher M, et al. MR imaging contrast enhancement based on intermolecular zero quantum coherences[J]. Science, 1998, 281: 247-252.

[8] Zhong J, Kwok E, Chen Z. fMRI of auditory stimulation with intermolecular double-quantum coherences (iDQCs) at 1.5 T[J]. Magn Reson Med, 2001, 45: 356-364. 

[9] Scha¨fer A, Jochimsen T, M?ller H. Functional magnetic resonance imaging with intermolecular double-quantum coherences at 3 T[J]. Magn Reson Med, 2005, 53: 1 402-1 408.

[10] Garrett-Roe S, Warren W S. Numerical studies of intermolecular multiple quantum coherences: High-resolution NMR in inhomogeneous fields and contrast enhancement in MRI[J]. J Magn Reson, 2000, 146: 1-13.

[11] Lee S, Richter W, Vathyam S, et al. Quantum treatment of the effects of dipole-dipole interactions in liquid nuclear magnetic resonance[J]. J Chem Phys, 1996, 105: 874-900.

[12] Cai C B, Chen Z, Cai S H, et al. A simulation algorithm based on Bloch equations and product operator matrix: Application to dipolar and scalar couplings[J]. J Magn Reson, 2005, 172: 242-253.

[13] Cai C B, Chen Z, Cai S H, et al. Finite difference simulation of diffusion behaviors under inter- and intra- molecular multiple-quantum coherences in liquid NMR[J]. Chem Phys Lett, 2005, 407: 438-443.

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基于分子间多量子相干的矢量场磁共振成像模拟

Simulation of Vector Field Magnetic Resonance Imaging Based on Inter-Molecular Multiple-Quantum Coherences

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