波段三维ESR成像系统的研制（Ⅴ）——灵敏度与分辨率实验及系统总性能指标

波谱学杂志 ›› 2004, Vol. 21 ›› Issue (2): 159-164.

波段三维ESR成像系统的研制（Ⅴ）——灵敏度与分辨率实验及系统总性能指标

吴可¹*，丛建波¹，张清俊¹，先宏¹，王长振¹，孙存普¹, 郑莹光²，许静²，董凤霞²，沈尔中²，徐玉书²

1. 军事医学科学院放射医学研究所，国家生物医学分析中心自由基与顺磁共振实验室，北京 100850; 2.吉林大学分析测试中心, 吉林长春 130022

收稿日期:2003-07-24 修回日期:2003-09-29 出版日期:2004-06-05 发布日期:2004-06-05
基金资助:
国家自然科学基金资助项目（29935080）

DEVELOPMENT OF L BAND THREE DIMENSIONAL ESR IMAGING SYSTEM(Ⅴ)——System Configuration and Performance Evaluation

WU Ke¹*, CONG Jian-Bo¹, ZHANG Qing-Jun¹, XIAN Hong¹, WANG Chang-Zhen¹, SUN Cun-Pu¹, ZHENG Ying-Guang², XU Jing², DONG Feng-Xia², SHEN Er-Zhong², XU Yu-Shu²

1.Institute of Radiation Medicine, Academy of Military Medical Science, National Center of Biomedical Analgsis, FR&ESR Lab, Beijing 100850, China; 2.Analytic and Measure Center, Jilin University, Changchun 130022, China

Received:2003-07-24 Revised:2003-09-29 Online:2004-06-05 Published:2004-06-05
Supported by:
国家自然科学基金资助项目（29935080）

摘要/Abstract

摘要：

实验确定了自行研制的L波段三维电子自旋共振成像（3D-ESRI）系统的检测灵敏度及成像分辨率指标. 用Tempo水溶液模型测量灵敏度结果表明：样品体积为10 mm, 高30 mm，测量浓度1×10^-4mol/L水溶液的信噪比为S/N=4∶1；加梯度磁场后，样品浓度需>5×10^-4 mol/L，样品体积为19 mm, 高30 mm时，获得的投影谱的信噪比可满足图像重建的需要. 用DPPH固体样品确定的成像分辨率结果<1 mm. 文中还对ESRI系统的
各项总体性能做了归纳总结.

关键词: 电子自旋共振, 3D-ESR成像, 灵敏度, 分辨率, 性能指标

Abstract:

The detection sensitivity and the achievable spatial resolution of a newly developed L-band three-dimensional ESR imaging system were evaluated. The detection sensitivity was measured using a group of samples of aqueous Tempo solution. A signal to noise ratio (S/N) of about 4∶1 was obtained on a cylindric al sample with diameter of 10 mm and height of 30 mm, which corresponds to the minimum detectable concentration of 1×10^-4mol/L. To obtain projections with sufficient S/N for imaging, a higher concentration of more than 5×10^-4mol/L and a larger sample size (diameter of φ19 mm and height of 30 mm) was needed. Measured on solid DPPH samples, the spatial resolution of imaging can reach about 1 mm. The general performance features of the ESRI system were also discussed in the paper.

Key words: ESR, 3D-ESRI, sensitivity, resolution, performance feature

中图分类号:

O482.53

吴可, 丛建波, 张清俊, 先宏, 王长振, 孙存普, 郑莹光, 许静, 董凤霞, 沈尔中, 徐玉书. 波段三维ESR成像系统的研制（Ⅴ）——灵敏度与分辨率实验及系统总性能指标[J]. 波谱学杂志, 2004, 21(2): 159-164.

WU Ke, CONG Jian-Bo, ZHANG Qing-Jun, XIAN Hong, WANG Chang-Zhen, SUN Cun-Pu, ZHENG Ying-Guang, XU Jing, DONG Feng-Xia, SHEN Er-Zhong, XU Yu-Shu. DEVELOPMENT OF L BAND THREE DIMENSIONAL ESR IMAGING SYSTEM(Ⅴ)——System Configuration and Performance Evaluation[J]. Chinese Journal of Magnetic Resonance, 2004, 21(2): 159-164.

参考文献

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