磁振灌流造影：对“流动敏感交互反转恢复”的评论

摘要/Abstract

摘要：

磁振造影在过去的数十年內取得了长足的进步，除了可提供生物解剖构造的资讯外，如今更可以进行组织灌流造影. 磁振灌流造影主要可分成2种：动态磁感对比（Dynamic susceptibility Contrast）和动脉标记（Arterial Spin Labeling）. 相较于动态磁感对比，动脉标记能非侵入性地观测灌流. 动脉标记包括了数种技术：如CASL (continuous arterial spin labeling), EPISTAR (echo planar imaging and signal targeting with alternating radiofrequency), PICORE (proximal inversion with a control for off-resonance effects) 和 FAIR (flowsensitive alternating inversion recovery). 该文主要提供流动磁感交互反转恢复（FAIR）技术的综合介绍，包括其理论基础和实践，特别针对T₁法在FAIR定量上的使用. 定量上的困难亦将会在文章中被讨论. 文章的最后总结FAIR之实际应用情形.

关键词: MRI, 灌流造影, FAIR, T₁定量

Abstract:

Over the past decades, Magnetic Resonance Imaging (MRI) has evolved into a modality that offers perfusion imaging in addition to anatomy. Two principal methods of MR perfusion imaging exist: Dynamic Susceptibility Contrast (DSC) and Arterial Spin Labeling (ASL). DSC has been applied more widely than ASL; however, complete noninvasive assessment is only attained by using ASL. There are numerous variants of ASL, including CASL (continuous arterial spin labeling), EPISTAR (echo planar imaging and signal targeting with alternating radiofrequency), PICORE (proximal inversion with a control for off-resonance effects) and FAIR (flow-sensitive alternating inversion recovery). This review aims to provide a comprehensive overview of FAIR technique, including theoretical background and implementations, in particular the T₁ method for FAIR quantification. The problems and pitfalls involved in the quantification model revisited. Finally, a brief summary of applications is presented.

Key words: MRI, perfusion imaging, FAIR, T₁ quantification

中图分类号:

R445.2

萧庭毅, 张程. 磁振灌流造影：对“流动敏感交互反转恢复”的评论[J]. 波谱学杂志, 2010, 27(3): 289-297.

Tiing-Yee SIOW, Chen CHANG. MR Perfusion Imaging: A Review of Flow Sensitive Alternating Inversion Recovery (FAIR) Technique[J]. Chinese Journal of Magnetic Resonance, 2010, 27(3): 289-297.

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