波谱学杂志 ›› 2005, Vol. 22 ›› Issue (4): 437-456.

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13C NMR在新型灵芝三萜类化合物的应用

  

  1. 1.中国科学院 昆明植物研究所, 植物化学和西部植物资源持续利用国家重点实验室,云南 昆明 650204;
    2.云南民族大学 化学与生物技术学院,云南 昆明 650031
  • 收稿日期:2005-05-16 修回日期:2005-07-11 出版日期:2005-12-05 发布日期:2005-12-05
  • 基金资助:

    中国科学院知识创新工程重要方向(KSCZX-SW-301-08)和西部之光联合学者计划资助项目.

13C NMR Chemical Shifts of Ganoderma Triterpenoids: A Meta-Analysis

  1. 1.State Key Laboratory Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, China;
    2.School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, China
  • Received:2005-05-16 Revised:2005-07-11 Online:2005-12-05 Published:2005-12-05
  • Supported by:

    中国科学院知识创新工程重要方向(KSCZX-SW-301-08)和西部之光联合学者计划资助项目.

摘要:

高等真菌灵芝属的子实体作为著名的中药,灵芝三萜类化合物是中药灵芝主要活性化学成分,近年来灵芝三萜类化合物仍然不断被大量发现, 而且结构越来越新奇. 本文总结了10年来文献报道灵芝三萜化合物的13C NMR化学位移,找出了一些规律, 对进行灵芝三萜化合物类结构的研究,将提供十分便捷的途径.

关键词: 13C NMR, 灵芝, 三萜化合物,  化学位移, 结构分析

Abstract:

The fruiting bodies of higher Ganoderma are well-known traditional Chinese medicines. The results of many previous studies have indicated that Ganoderma triterpenoids found in Ganoderma sp. are the main bioactive components. In recent years, a great number of novel triterpenoids with unique chemical structures has been isolated from Ganoderma.13C NMR is a powerful tool to determine the structure of Ganoderma triterpenoids. In this paper, a meta-analysis was performed on previously reported 13C NMR chemical shifts of triterpenoids and another substances isolated from Ganoderma and on their assignment. The characteristics of and interpretation rules for the 13C NMR spectra of these compounds were discussed. The results obtained in this study should be useful for future studies investigating the chemical structures, configuration and conformation of Ganoderma triterpenoids.

Key words: 13C NMR, Ganoderma, Ganoderma triterpenoids, chemical shift, chemical structure

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