13C NMR在新型灵芝三萜类化合物的应用

摘要/Abstract

摘要：

高等真菌灵芝属的子实体作为著名的中药，灵芝三萜类化合物是中药灵芝主要活性化学成分，近年来灵芝三萜类化合物仍然不断被大量发现，而且结构越来越新奇. 本文总结了10年来文献报道灵芝三萜化合物的¹³C NMR化学位移，找出了一些规律，对进行灵芝三萜化合物类结构的研究，将提供十分便捷的途径.

关键词: ¹³C NMR, 灵芝, 三萜化合物, 化学位移, 结构分析

Abstract:

The fruiting bodies of higher Ganoderma are well-known traditional Chinese medicines. The results of many previous studies have indicated that Ganoderma triterpenoids found in Ganoderma sp. are the main bioactive components. In recent years, a great number of novel triterpenoids with unique chemical structures has been isolated from Ganoderma.¹³C NMR is a powerful tool to determine the structure of Ganoderma triterpenoids. In this paper, a meta-analysis was performed on previously reported ¹³C NMR chemical shifts of triterpenoids and another substances isolated from Ganoderma and on their assignment. The characteristics of and interpretation rules for the ¹³C NMR spectra of these compounds were discussed. The results obtained in this study should be useful for future studies investigating the chemical structures, configuration and conformation of Ganoderma triterpenoids.

Key words: ¹³C NMR, Ganoderma, Ganoderma triterpenoids, chemical shift, chemical structure

中图分类号:

O482.53

乔英, 杨叶昆, 董学畅, 邱明华. ¹³C NMR在新型灵芝三萜类化合物的应用[J]. 波谱学杂志, 2005, 22(4): 437-456.

QIAO Yang, YANG Ye-Kun, DONG Xue-Chang, QIU Ming-Hua. ¹³C NMR Chemical Shifts of Ganoderma Triterpenoids: A Meta-Analysis[J]. Chinese Journal of Magnetic Resonance, 2005, 22(4): 437-456.

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¹³C NMR在新型灵芝三萜类化合物的应用

¹³C NMR Chemical Shifts of Ganoderma Triterpenoids: A Meta-Analysis

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