用于小口径5 T磁共振成像系统的梯度线圈和1H/13C双共振射频线圈研制

doi:10.11938/cjmr20243100

波谱学杂志 ›› 2024, Vol. 41 ›› Issue (3): 245-256.doi: 10.11938/cjmr20243100

用于小口径5 T磁共振成像系统的梯度线圈和¹H/¹³C双共振射频线圈研制

易鹏¹, 曹丽¹, 黄臻¹, 程鑫², 王佳鑫², 陈黎², 陈方²^,³, 鲍庆嘉²^,³, 张志²^,³^,^*(), 刘朝阳²^,³^,^#()

1.武汉轻工大学电气与电子工程学院, 湖北武汉 430023
2.波谱与原子分子物理国家重点实验室，武汉磁共振中心（中国科学院精密测量科学与技术创新研究院），湖北武汉 430071
3.中国科学院大学，北京 100049

收稿日期:2024-03-13 出版日期:2024-09-05 在线发表日期:2024-03-29
通讯作者: *Tel: 027-87199686, E-mail: zhangzhi@apm.ac.cn; #Tel: 027-87198790, E-mail: chyliu@apm.ac.cn.
基金资助:
国家重点研发计划项目(2023YFE0113300);国家重点研发计划项目(2022YFF0707000);中国科学院磁共振技术联盟科研仪器设备研制项目(2021-GZL001);中国科学院基础与交叉前沿科研先导专项(XDB0540300);国家自然科学基金项目(22327901);国家自然科学基金项目(81627901);国家自然科学基金项目(22374158);国家自然科学基金项目(22127801);国家自然科学基金项目(21927801);国家自然科学基金项目(12205352);国家自然科学基金项目(22204168);中国科学院精密测量科学与技术创新研究院交叉培育项目(S21S4101);中国科学院科研仪器研制项目(YJKYYQ20190032)

Development of Gradient Coils and ¹H/¹³C Dual-resonance RF Coils for a Small-bore 5 T MRI System

YI Peng¹, CAO Li¹, HUANG Zhen¹, CHENG Xin², WANG Jiaxin², CHEN Li², CHEN Fang²^,³, BAO Qingjia²^,³, ZHANG Zhi²^,³^,^*(), LIU Chaoyang²^,³^,^#()

1. School of Electrical and Electronic Engineering, Wuhan Polytechnic University, Wuhan 430023, China
2. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan (Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences), Wuhan 430071, China
3. University of Chinese Academy of Sciences, Beijing 100049, China

Received:2024-03-13 Published:2024-09-05 Online:2024-03-29
Contact: *Tel: 027-87199686, E-mail: zhangzhi@apm.ac.cn; #Tel: 027-87198790, E-mail: chyliu@apm.ac.cn.

摘要/Abstract

摘要：

基于自主研制的5 T磁共振成像系统和¹³C代谢磁共振成像研究需求，设计了一种小口径磁共振成像梯度线圈和¹H/¹³C双共振射频线圈系统．其中梯度线圈设计采用有限差分流函数方法，射频线圈设计为马鞍线圈结合表面线圈的双共振方案．采用有限元方法对磁场分布进行了数值模拟分析，成功研制出一套用于小口径5 T ¹³C磁共振成像的梯度与射频线圈，并利用自主研制的5 T磁共振成像系统平台验证了设计方案的可行性，经过实验测试采集到¹³C标记的尿素水模磁共振图像和小鼠头部¹H磁共振图像，为后续开展基于动态核极化的¹³C磁共振代谢成像奠定了基础．

关键词: 高场磁共振成像, ¹³C代谢磁共振成像, 梯度线圈, ¹H/¹³C双共振线圈, 马鞍线圈, 表面线圈

Abstract:

Based on the independently developed 5 T magnetic resonance imaging (MRI) system and research needs of¹³C metabolic MRI, a gradient coil and ¹H/¹³C dual resonance radiofrequency (RF) coil system for small-bore MRI were designed. The gradient coil was designed by using the finite-difference stream function method, and the RF coil was designed as a saddle coil combined with a surface coil in a dual-resonance scheme. Numerical simulation analysis of the magnetic field distribution was carried out by using the finite-element method, and a set of gradient and RF coils for small-bore 5 T ¹³C MRI was successfully developed. The feasibility of the design scheme was verified using a home-made 5 T MRI system, and the magnetic resonance images of ¹³C-labeled urea phantom and ¹H magnetic resonance images of mice head were acquired by experimental tests, which lays a foundation for ¹³C metabolic MRI based on dynamic nuclear polarization in the future.

Key words: high-field MRI, ¹³C metabolic MRI, gradient coil, ¹H/¹³C dual resonance coil, saddle coil, surface coil

中图分类号:

O482.53

易鹏, 曹丽, 黄臻, 程鑫, 王佳鑫, 陈黎, 陈方, 鲍庆嘉, 张志, 刘朝阳. 用于小口径5 T磁共振成像系统的梯度线圈和¹H/¹³C双共振射频线圈研制[J]. 波谱学杂志, 2024, 41(3): 245-256.

YI Peng, CAO Li, HUANG Zhen, CHENG Xin, WANG Jiaxin, CHEN Li, CHEN Fang, BAO Qingjia, ZHANG Zhi, LIU Chaoyang. Development of Gradient Coils and ¹H/¹³C Dual-resonance RF Coils for a Small-bore 5 T MRI System[J]. Chinese Journal of Magnetic Resonance, 2024, 41(3): 245-256.

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线圈方向	电感/μH	电阻/Ω	效率/(mTm^-1A^-1)	线性度	G_max/(T/m)	切换率/(T/m/s)
x	66.71	0.9	13.9184	0.99951	0.82	10000
y	68.68	0.9	13.0022	0.99758	0.8	9756.1
z	65.33	1.1	14.7408	0.99978	1	12195.1

用于小口径5 T磁共振成像系统的梯度线圈和¹H/¹³C双共振射频线圈研制

Development of Gradient Coils and ¹H/¹³C Dual-resonance RF Coils for a Small-bore 5 T MRI System

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