全开放式单边核磁共振技术研究及系统开发

doi:10.11938/cjmr20140404

波谱学杂志 ›› 2014, Vol. 31 ›› Issue (4): 488-503.doi: 10.11938/cjmr20140404

• 磁共振仪器研制技术进展专栏 • 上一篇下一篇

全开放式单边核磁共振技术研究及系统开发

汪红志^1,2*，刘翔^1，苗志英^1，陈珊珊^2，施群雁^1，徐罗元^3，陆治勇^3，刘利荣^3，杨培强³

1. 上海理工大学，医学影像工程研究所，上海 200093；2. 上海医疗器械高等专科学校，上海 200093；3. 苏州纽迈电子科技有限公司，江苏苏州 215163

收稿日期:2014-03-16 修回日期:2014-10-30 出版日期:2014-12-05 发布日期:2014-12-05
通讯作者: 汪红志 E-mail:wanghzhi2000@sina.com
作者简介:汪红志(1975-)，男，湖北黄冈人，博士，副教授，无线电物理专业. 电话：021-65485551，E-mail：wanghzhi2000@sina.com. *通讯联系人.
基金资助:
国家重大科学仪器设备开发专项资助项目(2013YQ170463).

Design and Construction of a Fully-Opened Unilateral Nuclear Magnetic Resonance System

WANG Hong-zhi^1,2*，LIU Xiang¹，MIAO Zhi-ying¹，CHEN Shan-shan²，SHI Qun-yan¹，XU Luo-yuan³，LU Zhi-yong³，LIU Li-rong³，YANG Pei-qiang³

1. University of Shanghai for Science and Technology, Shanghai, 200093, China;
2. Shanghai Medical Instrumentation College, Shanghai, 200093, China;
3. Suzhou Niumag Corporation Ltd, Suzhou, 215163, China

Received:2014-03-16 Revised:2014-10-30 Online:2014-12-05 Published:2014-12-05
About author:*Corresponding author：WANG hong-zhi, Tel: 021-65485551, E-mail: wanghzhi2000@sina.com.
Supported by:
国家重大科学仪器设备开发专项资助项目(2013YQ170463).

摘要/Abstract

摘要：

为了在单边磁体产生的逸散磁场中实现核磁共振技术，信号检测深度能满足相关应用需求，该文分析了非均匀磁场下的核磁共振技术条件，确定射频场目标，设计了单边平面射频线圈和探头，搭建出一套单边核磁共振实验系统．探头具有短脉宽(90°脉宽2.5 μs)，系统死时间短(10 μs)的特点，可实现15 μs 的半回波时间．应用该系统，在15.3 T/m 的巨大梯度磁场下，实现接近5 mm 厚度的信号检测，并利用单边磁体的自然梯度磁场，开展了恒定梯度磁场下的扩散测量方法探索．结果表明，该系统可满足需要一定探测深度的领域的应用需求．

关键词: 单边核磁共振系统, 平面线圈, SGSE-CPMG 序列, T₂ 弛豫时间, 扩散系数

Abstract:

The goal of the study is to design and construct a system that can be used to detect magnetic resonance signals generated in the stray magnetic field produced by fully-opened unilateral magnets. The radiofrequency (RF) probe was carefully designed to meet the detection depth requirement for specific applications, and tested on a unilateral nuclear magnetic resonance experiment system. The probe had a 90º pulse width as short as 2.5 s. The whole system has a short system dead time (i.e., 10 s), and the minimum half echo time was 15 s. The SGSE-CPMG experiment was performed on the system to acquire signals from a depth of 5 mm under a constant B0 gradient of 15.3 T/m. Diffusion coefficients were measured under the constant B0 gradient.

Key words: unilateral NMR system, planar coil, SGSE-CPMG sequence, T₂ relaxation time, diffusion coefficient

中图分类号:

O482.53

汪红志1,2*，刘翔1，苗志英1，陈珊珊2，施群雁1，徐罗元3，陆治勇3，刘利荣3，杨培强3. 全开放式单边核磁共振技术研究及系统开发[J]. 波谱学杂志, 2014, 31(4): 488-503.

WANG Hong-zhi1,2*，LIU Xiang1，MIAO Zhi-ying1，CHEN Shan-shan2，SHI Qun-yan1，XU Luo-yuan3，LU Zhi-yong3，LIU Li-rong3，YANG Pei-qiang3. Design and Construction of a Fully-Opened Unilateral Nuclear Magnetic Resonance System[J]. Chinese Journal of Magnetic Resonance, 2014, 31(4): 488-503.

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全开放式单边核磁共振技术研究及系统开发

Design and Construction of a Fully-Opened Unilateral Nuclear Magnetic Resonance System

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