核磁共振扩散测量和q-空间成像进展

摘要/Abstract

摘要：

在过去的近半个世纪，NMR扩散测量在理论和实践方面都不断取得进展,使得测量更加可靠和准确，并能获取越来越多的信息. 随着扩散测量技术的发展，其科学应用范围也不断增加，覆盖从物理化学到临床医学等各个领域. NMR扩散测量不仅能提供分子的平移运动动力学信息，而且也可以提供影响平移运动的局部几何结构的信息，后一种应用通常称为q-空间成像. 该综述聚焦于过去10年中的NMR扩散研究方面一些重大的进展.

关键词: 背景磁场梯度, 平移扩散, J-演化, 脉冲磁场梯度磁共振, q-空间成像, 单线态, 溶剂信号压制

Abstract:

NMR diffusion measurements have been undergoing continuous theoretical and practical development for more than four decades leading to more robust and accurate measurements and the ability to extract increasingly diverse information. Concomitant with this development has been applications ranging across ever more areas of science ranging from physical chemistry to clinical medicine. NMR diffusion measurements can provide information on not only the translational dynamics of a species but also on the local geometrical structures which influence translational motion, when used for the latter case such measurements are often referred to as q-space imaging. This review focuses on some of the significant developments in this area over the last decade.

Key words: background gradients, diffusion, J-evolution, PGSE NMR, q-space imaging, singlet spin states, solvent suppression

中图分类号:

O482.53

卜威廉, Tim STAIT-GARDNER, Allan M. TORRES, 郑钢. 核磁共振扩散测量和q-空间成像进展[J]. 波谱学杂志, 2010, 27(3): 267-288.

William S. PRICE, Tim STAIT-GARDNER, Allan M. TORRES, ZHENG Gang. Developments in NMR Diffusion Measurements and q-Space Imaging[J]. Chinese Journal of Magnetic Resonance, 2010, 27(3): 267-288.

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