波谱学杂志 ›› 2006, Vol. 23 ›› Issue (1): 89-94.

• 研究简报 • 上一篇    下一篇

几种氮氧自由基与β-环糊精及其衍生物作用的EPR研究

  

  1. 甘肃中医学院,甘肃  兰州 730000
  • 收稿日期:2005-06-22 修回日期:2005-09-05 出版日期:2006-03-05 发布日期:2006-03-05
  • 基金资助:

    国家自然科学基金资助项目(29971026)和甘肃省教委立项课题(2002-03).

Inclusion Complexes of Nitroxide Radicals with β-Cyclodextrin and 2- Hydroxypropyl β-Cyclodextrin in Aqueous Solution Studied  by EPR Spectroscopy

  1. Gansu College of Traditional Chinese Medicine, Lanzhou, Gansu 730000,  China
  • Received:2005-06-22 Revised:2005-09-05 Online:2006-03-05 Published:2006-03-05

摘要:

测定了三种氮氧自由基与环糊精相互作用的EPR波谱,计算了波谱参数. 结果表明:与环糊精作用后,自由基的超精细分裂常数(an) 值及旋转相关时间(τc)都有规律变化,由此探讨了氮氧自由基与环糊精相互作用位点及作用力大小.

关键词: EPR,  , 包合作用, 环糊精, 氮氧自由基

Abstract:

It was found in this study that the ESR spectra of three nitroxide radicals, 4-hydroxy-2,2,6,6-tetramethyliperidine-1-oxyl (R1), 4-azido-2,2,6,6-tetramethyliperdine-1-oxyl (R2) and 4-oxybenzene-sulfonyl-2,2,6,6-tetramethyliperidene-1-oxyl (R3), show distinctive changes in rotational correlation time τC and hyperfine splitting constants aN when included in β-cyclodextrin (β-CD) and 2-hydroxypropyl-β-CD in aqueous solution. Based on the EPR results, it is suggested that the steric factors and polarity of the functional groups affect the inclusion reaction.

Key words: EPR, inclusion complexes, cyclodextrin, nitroxide radical

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