波谱学杂志 ›› 1999, Vol. 16 ›› Issue (5): 417-422.

• 研究论文 • 上一篇    下一篇

应用2D NMR技术研究原七叶树皂甙甙元的结构

杨秀伟, 赵静   

  1. 北京医科大学天然药物及仿生药物国家重点实验室, 北京 100083
  • 收稿日期:1999-04-26 修回日期:1999-06-04 出版日期:1999-10-05 发布日期:2018-01-13
  • 作者简介:杨秀伟,男,1958年出生,日本国富山医科药科大学药学博士,教授

STRUCTURE ELUCIDATION OF PROTOAESCIGENIN BY 2D NMR TECHNIQUES

Yang Xiuwei, ZhaoJing   

  1. Beijing Medical University, National Laboratory of Naturaland Biomimetic Drugs, Beijing 100083
  • Received:1999-04-26 Revised:1999-06-04 Online:1999-10-05 Published:2018-01-13

摘要: 原七叶树皂甙甙元是七叶树皂甙经温和酸水解得到的皂甙甙元,系多羟基齐墩果烷三萜类化合物.应用2D NMR技术:1H-1H COSY、HMQC、HMBC和NOESY全归属原七叶树皂甙甙元碳和氢质子信号,为该类型化合物的结构签定提供光谱学依据.

关键词: 原七叶树皂甙甙元, 2DNMR, 碳氢信号全归属

Abstract: Protoaescigenin is a multihydroxy oleanane-type triterpene yielded by mildacid hydrolysis of escin Ia. A series of 2D NMR techniques, including 1H-1H COSY, HMQC, HMBC and NOESY were applied in detailed assig nments of all their carbon and proton sig nals.

Key words: Protoaescigenin, 2D NMR, Full assignments of 1H and 13C NMR signals